Dodecyl phosphocholine

The quadrupolar 2H spin-lattice relaxation of specifically deuterated surfactants, such as the methyl deuterated n-alkyl phosphocholine surfactants, also shows a concentration dependence. The CMC of dodecyl phosphocholine was determined by exploiting the difference in the 2H spin-lattice relaxation times of the monomers versus the micellar state.68 Quadrupole splittings of 14N were also used to characterize the micellization process of short-chain perfluoro-carboxylic acid salts.69... 

Dodecyl phosphocholine micelles in solution are useful and well characterized as a model membrane system for solution NMR studies. To access the membrane-induced conformation and orientation of cardiotoxins, the interaction of the p-type cardiotoxin II from Naja oxiana snake venom with perdeuterated dodecyl phosphocholine was studied by H NMR spectroscopy and diffusion measurements.247 2D NMR is an efficient tool and has been widely used to study the interaction of dodecyl phosphocholine with peptides and protein.248-250 2D... 

C17H39N04P 352 Z 20 0.0013 7 dodecyl trimethylammonioethyl phosphate or dodecyl phosphocholine... 

Other novel bicelle systems composed of a mixture of l,2-di-0-dodecyl-sn-glycero-3-phosphocholine and 3-(chloramidopropyl)dimethylammonio-2-hydroxyl-l-propane sulfonate have been designed to orient proteins at low pH values and over wide temperature ranges [25]. 

FIGURE 3.1 Some examples of common surfactant molecules, from top anionic surfactant SDS (sodium dodecyl sulfate, also commonly known as sodium lauryl sulfate) cationic surfactants CTAB (hexadecyltrimethylammonium bromide), DDAB (didecyidimethylammonium bromide) commercial nonionic detergent Triton X-100 and zwitterionic lipid DOPC (1,2-dioleoyl-sn-glycero-3-phosphocholine). 

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