DNA binding ligands

Pindur U., Lemster T. Recent Advances in the Synthesis of Carbazoles and Anellated Indoles With Antitumor Activity DNA-Binding Ligands and Protein Kinase C Inhibitors Recent Res. Dev. Org. Bioorg. Chem. 1997 1 33-54 Keywords Diels-Alder reactions of a 4,7-dioxo-indole with carbodienophiles... 

Zimmer, C. and U. Wahnert. Nonintercalating DNA-binding ligands Specificity of the interaction and their use as tools in biophysical, biochemical, and Biological investigations of the genetic material. Prog. Biophy. Molec. Biol. 1986, 47, 31— 112. 

Ginsburg, H., E. Nissani, M. Kmgliak, and D.H. Williamson. Selective toxicity to malaria parasites by non-intercalating DNA-binding ligands. Mol. Biochem. Parasitol. 1993, 58, 7-15. 

McBryant, S.J., E.E. Baird, J.W. Trauger, P.B. Dervan, and J.M. Gotteseeld. Minor groove DNA-protein contacts upstream of a tRNA gene detected with a synthetic DNA binding ligand. /. Mol. Biol. 1999, 286, 973-981. 

C.L. White, C. Melander, J.M. Gotteseeld, P. B. Dervan, and K. Luger Crystal stmctures of nucleosome core particles in complex with minor groove DNA-binding ligands. J. Mol. Biol. 2003, 326, 371-380. 

Dervan PB, Poulin-Kerstien AT, Fechter EJ, Edelson BS (2005) Regulation of Gene Expression by Synthetic DNA-Binding Ligands. 253 1-31 Dias N, Vezin H, Lansiaux A, Badly C (2005) Topoisomerase Inhibitors of Marine Origin and Their Potential Use as Anticancer Agents. 253 89-108 DiMauro E, see Saladino R (2005) 259 29-68... 

Tsujita S, Tanada M, Kataoka T, Sasaki S (2007) Equilibrium shift by target DNA substrates for determination of DNA binding ligands. Bioorg Med Chem Lett 17 68-72... 

Dervan PB, et al. Regulation of gene expression by synthetic DNA-binding ligands. Top. nobreak Curr. Chem, 2005 253 1-31. 

Dickinson LA, Guhzia RJ, Trauger JW, Baird EE, Mosier DE, Gottesfeld JM, Dervan PB. Inhibition of RNA polymerase II transcription in human cells by synthetic DNA-binding ligands. Proc. Natl. Acad. Sci. U.S.A. 1998 95 12890-12895. 

Functional data - e.g. DNA binding, ligands, metals, catalysis, etc. 

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