Dithiopropionic acid

Amino acid composition was analysed as described by Barkholt and Jensen (6). Cysteine was determined after derivatisation with 3,3 -dithiopropionic acid. Tryptophan was not determined. 

Dithiocarboxylic acid derivatives also provide a useful route to dithioketene acetals (another name for ketene dithioacetals).Treatment of dithiopropionic acid (376) with excess LDA (for 0-alkylation reactions... 

Thiol modified HA is generally prepared by conjugation with a disulfide containing molecules such as cystamine or a 3,3 -dithiopropionic acid dihydrazide that is coupled to HA using EDC chemistry. Reduction of disulfide bonds by dithiothreitol yields the desired thiol derivative. The thiol derivatives of HA has been extensively used to develop... 

Among miscellaneous recent papers concerned with the reactivity of thiono- and dithio-acids and -esters [including those reporting the synthesis of 1,3-thiazine derivatives from 2-iminocyclopentanedithiocarboxylic acid, the use of chlorothionoformates for the conversion of aldoximes into nitriles, and the rapid, exothermic reaction of ethyl dithiopropionate with t-butoxy-bis(dimethylamino)methane, yielding 3-dimethylamino-2,7VA -trimethyl-thioacrylamide (181 = R = R = Me) ] is a... 

Dithiocarboxylic acid esters. 1.5-2 moles of phosgene passed at 25-30° into a soln. of propionic acid piperidide in toluene, and the product isolated after 4-5 hrs. propionic acid piperidide chloride (Y 90-95%) suspended in abs. ether, treated at 0° with ethyl mercaptan, the ether removed, the residue treated with dimethylformamide and pyridine, HgS introduced 4 hrs. at 0°, and allowed to stand several hrs. at room temp. ethyl dithiopropionate (Y 86%). F. e., also thionocarboxylic acid esters by initial treatment with alcohol, isolation of thiolic acid esters, and f. reactions, also ring closures to hetero-cyclics, s. H. Eilingsfeld, M. Seefelder, and H. Weidinger, B. 96, 2671 (1963). 

The combined introduction of an inhibitor, which terminates chains, and a substance, which decomposes hydroperoxides, is widely used for the more efficient retardation of oxidation processes in polyolefins, resins, lubricants, and other materials. Various phenols, bisphenols, and aromatic amines are applied as an acceptor of RO 2, and aryl phosphites, esters of thiopropionic acid, dialkyl dithiopropionates and thiophosphates of zinc and nickel, and other similar compounds are introduced to... 

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