Dissolution, from drug surfactant mixtures

Another approach in using a lipid-based formulation is to micronize the lipid with the dissolved drug to create a microemulsification. This allows an increased surface area available for the dissolution of the drug from the lipid phase. In these mixtures, a surfactant is usually added to improve the ability of oil to accommodate a hydrophobic drug in solution, and the resulting liquid is almost clear. Also a surfactant can function in the GI tract to help disperse the liquid vehicle on dilution. This allows the drug (dissolved in oil droplets/surfactant) to spread readily along the GI tract. 

---