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Dissolution-controlled release, oral drug

In recent years, interest in multiple-layered tablets as an oral controlled release system has increased. Multiple-layered tablets have some obvious advantages compared with conventional tablets. In addition to avoiding chemical incompatibibties of formulation components by physical separation, release profiles may be modified by combining layers with different release patterns or by combining slow release with immediate release layers. If the core layer of multilayered tablet is completely covered by a surrounding layer, the product is commonly referred to as a dry-coated tablet. An example is the Smartrix tablet, in which the release profile of a drug is determined by the increase in release surface caused by erosion (dissolution) of the cover layers.39... [Pg.168]

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Controlled drug release

Controlled release

Dissolution-controlled release

Dissolution-controlled release, oral drug delivery

Drug dissolution

Drug release

Drug release control

Oral drugs

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