Diseases associated with expression autism

Although there obviously is individual variability in the expression of brain nAChRs in the population, altered expression of some nAChRs relative to healthy controls is associated with several neuropsychiatric disorders. The best-studied example of low nAChR expression in brain and disease is schizophrenia. A second example discussed is autism. 

The inability to express oneself through either speech or writing is perhaps the most limiting of physical disabilities. Meaningful participation in life requires the communication of information, desires, needs, feelings, and aspirations. The lack of full interpersonal communication results from a variety of congenital and acquired disabilities, including but not limited to amyotrophic lateral sclerosis, aphasia, autism, brain injury, cerebral palsy, and Parkinson s disease. Also, the use of natural speech to communicate maybe interrupted due to hospitalization. The complex communication disorders associated with these conditions substantially reduce an individual s quality of life and potential for education, employment, and independence. 

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