Disease changing patterns

Cohen ML. Changing patterns of infectious disease. Nature 2000 406[6797] 762-767. 

The changing pattern of disease, coupled with a steady increase in our understanding of physiological and biochemical mechanisms and macromolecular structure, will continue to provide new targets for drug design. 

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Cohen, M.L., Changing patterns of infectious diseases. Nature, 406, 762, 2000. 

Even at these dramatically diminished prevalence rates, we cannot dismiss the rate of occurrence of these illnesses. Although the prevalence of disease is substantially less, health issues continue to be recognized, particularly in the older or retired worker. Perhaps the most consequential of these dust diseases is asbestosis, the only major pneumoconiosis to demonstrate an increase in mortality over the past decade (Changing Patterns of Pneumo-... 

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