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Discovery research starting materials

It was very time-consuming to screen substances in animal tests for efficacy and to prepare lead analogues by classical synthesis. Therefore, it is not surprising that the researchers looked for alternatives. Today pharmaceutical companies apply computerized robotic systems in drug discovery. The starting point is the chemical library. This library does not contain books, but chemicals. Many companies keep small samples of all chemical compounds that they ever synthesized or extracted from the plant material. The amount of the samples is usually small and they are kept in microplates in dedicated temperature-controlled storage facilities. Chemical libraries of large pharmaceutical companies contain several million different compounds. [Pg.341]

See other pages where Discovery research starting materials is mentioned: [Pg.8]    [Pg.4]    [Pg.229]    [Pg.46]    [Pg.375]    [Pg.180]    [Pg.116]    [Pg.300]    [Pg.113]    [Pg.76]    [Pg.89]    [Pg.53]    [Pg.1198]    [Pg.578]    [Pg.2198]    [Pg.1229]    [Pg.193]    [Pg.330]    [Pg.69]    [Pg.102]    [Pg.64]    [Pg.95]    [Pg.203]    [Pg.208]    [Pg.427]    [Pg.38]    [Pg.167]    [Pg.193]    [Pg.19]    [Pg.2]    [Pg.417]    [Pg.351]    [Pg.9]    [Pg.17]    [Pg.5960]    [Pg.4]    [Pg.698]    [Pg.254]    [Pg.2]    [Pg.96]    [Pg.110]    [Pg.267]    [Pg.195]    [Pg.31]    [Pg.1152]    [Pg.183]    [Pg.43]    [Pg.2]    [Pg.1]   
See also in sourсe #XX -- [ Pg.157 ]



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