Dipyridamole drug interactions

Drug interactions Caution is called for when administering tenecteplase with drugs that affect platelet function such as aspirin, dipyridamole, clopidogrel, and glycoprotein Ilb/IIIa inhibitors. Administration of tenecteplase before, during, or after any of these drugs may increase the risk of... 

Drug interactions Methylxanthines e.g., theophylline) and dipyridamole are adenosine antagonists. 

There are no documented drug interactions, but garlic s antiplatelet effect might be dangerous in patients taking warfarin or antiplatelet agents such as aspirin, clopidogrel, ticlopidine, or dipyridamole. 

Drug/Lab test interactions Over the course of 24 months, patients treated with dipyridamole and aspirin combination therapy showed a decline (mean change from baseline) in hemoglobin of 0.25 g/dL, hematocrit of 0.75%, and erythrocyte count of 0.13 X 10 /mm2. 

In two of the five spontaneous bleeding episodes described in Heading 4, medications that can affect platelet function or prothrombin time (PT) (i.e., aspirin and warfarin) were involved. Because GB is known to be an inhibitor of PAF (41), in theory GB could interact with antiplatelet drugs (e.g., aspirin, nonsteroidal anti-inflammatory drugs, clopidogrel, ticlopidine, dipyridamole) or anticoagulants (e.g., warfarin, heparin). EGb 761 was shown to potentiate the antiplatelet effect of ticlopidine in rats (42). However, in two studies in humans, the coadministration of GB with warfarin had no effect on either international normalized ratio or warfarin metabolism (43,44). 

---