Dinoprostone

The intense activity in this field—it has been estimated that as many as a thousand analogs have been prepared to date-promises a number of drugs in the near future. At this writing, two prostaglandins are available for use by the clinician. Both these compounds, dinoprost (7, PGFaa) and dinoprostone (S, PGE2), are used for the termination of pregnancy in the second trimester. [Pg.27]

Acetoxolone aluminum salt Aluminum amalgam Dinoprostone Aluminum tert-butoxide Megestrol acetate Aluminum chloride Acebutolol... [Pg.1611]

Cj(,H420s 466-06-8) see Meproscillarin prostaglandin F2 9,1 l-bis(tetrahydropyranyl ether) (C30H50O7 67899-19-8) see Dinoprostone prostaglandin p2a ll,15-bis(tetrahydropyran-2-yl ether)... [Pg.2438]

Dinoprostone gel (Prepidil) 1 application (0.5 mg) every 6 hours Store in refrigerator and bring to room temperature... [Pg.730]

Dinoprostone vaginal insert Insert once (releases 0.3 mg per hour) ... [Pg.730]

Systematic review concludes that misoprostol shows greater efficacy versus dinoprostone, but this benefit is offset by a greater incidence of side effects.46 Compared with dinoprostone, misoprostol is associated with a higher incidence of uterine hyperstimulation, alterations in fetal heart rate, and fetal distress.46 Misoprostol also has been associated with uterine rupture in patients with previous delivery by cesarean section and should be avoided in this population.44... [Pg.734]

Despite these limitations to misoprostol s use, it is much cheaper than the dinoprostone products. The average cost of misoprostol is less than 1 per dose versus a cost of 65 to 75 for dinoprostone gel.45 At 165, the dinoprostone insert is more expensive than the dinoprostone gel but offers the advantage of quick removal should adverse events occur.45... [Pg.734]

Dinoprostone gel. Start monitoring 15 minutes prior to gel insertion and continue for 30 to 120 minutes after administration. [Pg.735]

Ritodrine relaxes the uterine muscle and is therefore indicated to prevent premature labour. Ergometrine, oxytocin and carboprost are all indicated to induce or augment labour by inducing uterine contractions and hence can be used to cause the uterus to contract after delivery. Dinoprostone is mostly used for the induction of labour. [Pg.244]

Dimethothiazine, 374 Dimethoxanate, 390 Dimethylpyrindene, 145 Dimethylthiambutene, 106 Dimetridazole, 240 Dinoprost, 27, 33, 34 Dinoprostone, 27, 30, 33, 35 Dioscorea, see Mexican yam Diosgenin, 156, 182 Dioxyline, 349 Diphenhydramine, 41 Diphenidol, 45 Diphenoxylate, 302 Diphenylhydantoin, 246 Di phepanol, 46 Dipipanone, 80 Dipiproverin, 94 Dipyridamole, 428 Displacement, bromine by nitro, 247... [Pg.480]

Dinoprostone (Cervidil Vaginal Insert, Prepidil Vaginal Gel, Prostin E2) [Prostaglandin/Abortifacient] WARNING Should... [Pg.135]

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