Dinophysis miles

A pair of peaks attributable to PTXs with a molecular weight of two less than that of PTX-2 were observed during LC-MS analyses of extracts obtained by solid-phase extraction of a Dinophysis bloom from the east coast of Norway. The compoimds were isolated from a bloom of D. acuta from the west coast of Norway and identified as PTX-12 (38,47-dehydroPTX-2) as a pair of equilibrating 36-epimers (Miles et al. 2004b). 

Miles, C.O., Wilkins, A.L., Mimday, R., Dines, M.H., Hawkes, A.D., Briggs, L.R., Sandvik, M., Jensen, D.J., Cooney, J.M., Holland, P.T., Quilliam, M.A., MacKenzie, A.L., Beuzenberg, V, and Towers, N.R. 2004a. Isolation of pectenotoxin-2 from Dinophysis acuta and its conversion to pectenotoxin-2 seco acid, and preliminary assessment of their acute toxici-ties. Toxicon 43, 1—9. 

Miles, C.O., Wilkins, A.L., Samdal, LA., Sandvik, M., Petersen, D, Quilliam, M.A., Naustvoll, L.J., Rundberget, T, Torg-ersen, T, Hovgaard, R, Jensen, D.J., Lundve, B., and Lindahl, O. 2004c. PTX-12, a new pectenotoxin from Dinophysis species and mussels in Scandinavia. In 5th International Conference on Molluscan Shellfish Safety, Galway, Ireland, June 14-18, Book of Abstracts, p. 17. 

Suzuki, T., Walter, J.A., LeBlanc, R, Mackinnon, S., Miles, C.O., Wilkins, A.L., Munday, R. et al.. Identification of pectenotoxin-11 as 345-hydroxypectenotoxin-2, a new pectenotoxin analogue in the toxic dinoflagellate Dinophysis acuta from New Zealand. Chem. Res. Toxicol.l9, 310, 2006. 

Miles, C.O., et al.. Isolation of pectenotoxin-2 from Dinophysis acuta and its conversion to pectenotoxin-2 seco acid, and preliminary assessment of their acute toxicides, Toxicon, 43,1, 2004. 

Miles, C.O. et al. Isolation and identification of pectenotoxins-13 and -14 from Dinophysis acuta in New Zealand, Toxicon 48, 152, 2006. 

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