6,8-Dinitro-3,4-dihydro

Cyclonite Oxide or 3,5-Dinitro-dihydro 1,3,5 -oxadiazine (names given by Blatt) l-Oxa-3, 5-dinitro-3,5-diazacyclohexane (name given by Jones Thorne) and 3,5-Dinitro-tetra-hydro-2H-l,3,5-oxad iazine (name given in CA) (called Oxyhexogene in Fr)... 

Benzo[6]furan, trans-3-acetoxy-2,3-dihydro-2-methyl-5,7-dinitro- H NMR, 4, 571 (713001805)... 

Die Elektrolyse von 2,2 -Dinitro-diphenylsulfid an Quecksilber fuhrt in saurem Milieu zum Diamin, sonst zum Dibenzo-1,4,5-thiadiazepin, das zum 9,10-Dihydro-Derivat (Klemmenspannung 40-65 V) weiter reduziert werden kann5 ... 

Recent examples of this synthesis are of two types. The first involves condensation of the activated phenol, 2-amino-4,6-dinitrophenol (346a) with 2-dimethyl-amino-3,3-dimethyl-3//-azirine (346b) (in MeCN, 0°C- 20°C, A, 24 h) to afford a separable mixture of four products, one of which was 2-dimethylamino-3,3-dimethyl-5,7-dinitro-3,4-dihydroquinoxaline (346c) ( 20% yield) and another its hydrolysis product, 3,3-dimethyl-5,7-dinitro-3,4-dihydro-2(l//)-quinoxalinone (346d) ( 8%) the mechanism of such condensations has been discussed. ... 

See 4-(2/-Ammonio-2/-carboxyethylthio)-5,7-dinitro-4,5-dihydro-benzofurazanide /V-oxide... 

Nitration of 206 with a mixture of potassium nitrate and sulfuric acid yielded a mixture of dinitro derivative 240 and oxidation product 46. Heating 206 with sodium borohydride led to hydrolysis to 208 rather than to any reduction product. On the other hand, reduction with zinc in cold acetic acid provided dihydro derivative 241, whereas catalytic hydrogenation over palladium on carbon provided tetrahydro derivative 242 (Scheme 59) [90JCS(P 1) 1463]. 

NONM lH-Indene, 6-ethyl-2, 3 dihydro-1, 1-dimethyl 5,7-dinitro... 

MSTR lH-Indene, 3-ethyl, 2, 3 -dihydro-1, 1,3, 5-tetramethyl 4, 6-dinitro... 

Dinitro-naphthalin wird mit Natriumboranat zum Salz des 8-Nitro-l-aci-nitro-l,4-dihydro-naphthalins reduziert, das unter Abspaltung von salpetriger Saure mit verschie-denen Diazonium-Salzen zu den entsprechenden -Arylazo-8-nitro-naphthalinen reagiert1 ... 

Die Umsetzung von 3,4-Dinitro-l-methyl-pyrrol mit eincm UberschuB an sekundaren Aminen wie Piperidin oder Morpholin ergibt 2,3-Dipiperidino(b7.w. Dimorpholino)-l-me-thyl-4-nitro-2,3-dihydro-pyrrol (85 bzw. 87%)z. 

High yields of tricyclic compounds, 4,8-dihalo- or 4,8-dinitro-substituted 1,1,3,3,5,5,7,7-octa-fluoro-5,7-dihydro-l//,3//-benzo[l,2-c 4,5-c ]difurans 13, are obtained by treatment of the dihalo- or dinitrobenzene-1,2,4,5-tetracarboxylic acids with sulfur tetrafluoride and hydrogen fluoride at elevated temperatures.132 141... 

Benzene, (cHLORO-teri-BuTYL)-, 32, 90 2-chloro-1, 3-dinitro-, 32, 23 ETHYNYL-, 30, 72 HEXAMETHYL-, 35, 73 1,2,3-trimethyl-, 34, 56 Benzeneboronic ACID, 39, 4 Benzeneboronic anhydride 39, 3 Benzenediazonium chloride, 32, 84 Benzenesulfenyl chloride, 36, 101 Benzenesulfonyl chloride, 31, 83 9,10-o-Benzenoanthracene, 9,10-dihydro-, 39, 75 Benzhydrol, 33, 11 Benzhydryl chloride, 39, 74 Benzidine, 36, 21... 

Reaction of 6-formyl-5,7,8,9-tetrahydro-ll//-pyrido[2,l-b]quinazolin-ll-one (135) with Clayfen [K-10 montmorillonite clay supported iron(III) nitrate] in boiling methylene chloride for 2.5 h gave a mixture of 6,6-dinitro-6,7,8,9-tetrahydro (136) and 6-formyl-8,9-dihydro-ll//-pyrido[2,l-6]-quinazolin-ll-ones (137) (90JOC6198). 

Reaction of ethyl 9-(dimethylaminomethylene)-4-oxo-6,7,8,9-tetrahy-dropyrido[ 1,2-a]pyrimidine-3-carboxylate 539 with Clayfen in refluxing dichloromethane for 2.5 hours afforded a mixture of 9-nitro-1,6,7,8-tetrahydro (534 R = 6-Me),9,9-dinitro-6,7,8,9-tetrahydro(535 R = Me), and ethyl 7,9-dinitro-l,6-dihydro-6-methyl-4//-pyrido[l,2-a]pyrimidine-3-carboxylate 540 in 50%, 12%, and 12% yields, respectively (90JOC6198). 

Vomicine is easily monobrominated, probably in position 3, ortho to the phenolic group (187). Mononitration may be achieved with dilute aqueous nitric acid, but is difficult and gives varying yields dihydro-vomicine on the other hand gives a dinitro derivative in very good yield (194). Nitric-concentrated sulfuric acid mixture at —18° oxidizes the aromatic ring (see Section IV, E, 2). 

C NMR spectra of 3-nitro-l,2,4-triazol-5-one and seven of its salts with different amines have been studied. The chemical shifts of C-3 and C-5 are independent of the nature of the cation (Table 3.21) [560], NMR spectra of 1-nitro-1,4-dihydro-1-7/-l,2,4-triazol-5-one, 5-(3-azido-l,2,4-triazol-3-yl)-3-nitro-l,2,4-triazoles [611], l-alkyl-3-nitro-l,2,4-triazol-5-one [612], some 3-nitro-2-methyl-l,2,4-triazolone derivatives [613-615], and their mono- and dinitro energetic salts [616] have been discussed. 

---