Dimethylsulfoxide water

Phosphoryl chloride Carbon disulflde, A,A-dimethylformamide, 2,5-dimethylpyrrole, 2,6-dimethyl-pyridine 1-oxide, dimethylsulfoxide, water, zinc... 

Figure 6-2. Curved Arrhenius plot for the hydrolysis of methyl trifluoroacetate in dimethylsulfoxide-water (mole fraction water = 0.973). ...

The curvature may be an artifact of a selection of nucleophiles of mixed structural types chosen to display a wide range in pAo. Buncel et al. ° varied pK by changing the solvent composition over a limited range rather than by changing the structure. They studied the reaction between X-C6H4-CT and p-nitrophenyl acetate in 40-90 mol% dimethylsulfoxide—water mixtures with just three X substituents... 

The heats of solution and dilution of electrolytes in nonaqueous-aqueous solvent mixtures have been limited mostly to alcohol-water systems and a few measurements in dimethylsulfoxide-water and dioxane-water mixtures (J, 2). The structural maximum in aqueous-organic solvents at high water content has been well established by a variety of techniques (3,4), but few systems have been explored over the whole composition range. 

P. Suppan, Time-resolved luminescence spectra of dipolar excited molecules in liquid and solid mixtures - dynamics of dielectric enrichment and microscopic motions, Faraday Discuss., (1988) 173-84 L. R. Martins, A. Tamashiro, D. Laria and M. S. Skaf, Solvation dynamics of coumarin 153 in dimethylsulfoxide-water mixtures Molecular dynamics simulations, J. Chem. Phys., 118 (2003) 5955-63 B. M. Luther, J. R. Kimmel and N. E. Levinger, Dynamics of polar solvation in acetonitrile-benzene binary mixtures Role of dipolar and quadrupolar contributions to solvation, J. Chem. Phys., 116 (2002) 3370-77. 

Using A -Bromosticcinimide in Dimethylsulfoxide/ Water A solution of 3.0 g (22 mmol) of 3-terr-butylcyclohex-ene in 50 mL of DMSO H,0 (95 5) is stirred with 4.3 g(24 mmol) of NBS at 20 JC for 1 h. The reaction mixture is diluted with H,0 and extracted with Et20 to yield 4.2 g of a mixture of the four possible bromohydrins. A sample of this mixture is treated with 1 M KOH in EtOH. After 30 min, dilution with H20. extraction with Et20 and evaporation to dryness gives a mixture of trans- and m-epoxide in a ratio of 82 18 (GC). 

Kudryashova EV, Visser AJWG, van Berkel WJH. Monomer formation and function of p-hydroxybenzoate hydroxylase in reverse micelles and in dimethylsulfoxide/water mixtures. Chem-BioChem. 2008 9 413-119. 

This argument is further supported by the very fast acylation of -cyclodextrin by bound p-nitrophenyl ferrocene acrylate (9) in dimethylsulfoxide-water. (60/40 v/v)... 

Several polycyclic aromatic hydrocarbons that are genotoxic were ozonized in acetone-water or dimethylsulfoxide-water solvents. In most cases, mutagenic or carcinogenic activity was entirely lost after a brief exposure to ozone, but in one case (7,12-dimethylbenz[a]anthracene, 82) a small number of animal tumors developed. 

This argument is further supported by the very fast acylation of y8-cyclodextrin by bound p-nitrophenyl ferrocene acrylate (9) in dimethylsulfoxide-water. (60/40 v/v) [18]. In the )8-cyclodextrin-(9) complex the acyl group of the ester rather than the leaving group is boimd to the cyclodextrin. The acylation of )8-cyclodextrin by this ester is accelerated by 750000-fold and the rate achieved is comparable with that for... 

R. N. Roy, W. Vernon, A. Bothwell, and J. Gibbons, J. Electrochem. Soc., 119, 694 (1972). Standard potentials of Ag AgCl electrode and related thermodynamic quantities in dimethylsulfoxide-water mixtures from 5 to 45°C. 

K. H. Khoo, J. Chem. Soc., 2932 (1971). The standard potentials of silver-silver halide electrodes and ion solvation in dimethylsulfoxide-water mixtures at 25°C. 

Lam, S. Y Benoit, R. L. Some thermodynamic properties of the dimethylsulfoxide-water and propylene carbonate-water systems at 25.deg.C. Can. J. Chem. 1974, 52, 718-722. 

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