4-dimethylaminophenyl phenyl

A laser flash photolytic study of the reaction between 2,2 -dipyridyl and tryptophan has been described. The primary photochemical step has been demonstrated to be pH independent and involves an electron transfer from the tryptophan to the dipyridyl triplet state. The triplet excited state of some peptide conjugates is produced on irradiation by a nanosecond laser flash. C-C Bond cleavage is the result of irradiation of the pinacols (214) in chloroform. This yields the corresponding aldehydes. The mechanism of the cleavage process has been shown to involve single electron transfer with chloroform as the electron acceptor. A study of intramolecular charge separation in aminophenyl(phenyl)acetylene and A, A-dimethylaminophenyl(phenyl)-acetylene has been reported. ... 

Ring closure of 2-chloro-l-phenethylpyridinium ion (247) (prepared in situ) to l,2-dihydro-3,4-benzoquinolizium ion involves intramolecular nucleophilic displacement of the chloro group by the phenyl 77-electrons. A related intermolecular reaction involving a more activated pyridine ring and more nucleophilic 7r-electrons is the formation of 4-( -dimethylaminophenyl)pyridine (and benzaldehyde) from dimethylaniline and 1-benzoylpyridinium chloride (cf. Section III,B,4,c). 

Dimethylaminophenyl)-3,4-dihydroquinoxaline gave 2-(p-dimethylamino-phenyl)quinoxaline (tetrachlorobenzoquinone, PhH, reflux, 1 h 76%).780... 

The photo-oxidation of the aryl-substituted cycloheptatrienes 7-(/ -methoxy-phenyl)cycloheptatriene and 7-, 1- and 3-(/ -dimethylaminophenyl)cycloheptatrienes to the corresponding radical cations in de-aerated acetonitrile solution was accomplished by electron transfer to the electronically excited acceptors 9,10-dicyanoanthracene, iV-methylquinolinium perchlorate, iV-methylacridinium perchlorate and l,T-dimethyl-4,4-bipyridinium dichloride. In the case of l- p-methoxyphenyl)cycloheptatriene (62), deprotonation of the radical cation occurs successfully, compared with back electron transfer, to give a cycloheptatrienyl radical (63) which undergoes a self-reaction forming a bitropyl. If the photooxidation is done in air-saturated acetonitrile solution containing HBF4 and one of the acceptors, the tropylium cation is formed. Back electron transfer dominates in the / -dimethylaminocycloheptatrienes and the formation of the cycloheptatrienyl radical is prevented. 

Antiprogestins, such as RU-486 (lift-hydroxy-11/3 (4 dimethylamino phenyl-1 )-17ry-(prop-l-ynyl)-estra-4.9-diene-3-one) (33) and ZK98299 1 l/J-(4-dimethylaminophenyl)-17a-hydroxy-17/j-(3-hydroxypropyl-13a-methyl-4,9-gonadien-3-one) represent a new class of drags for fertility regulation. Also, these drugs have potential applications in the treatment of uterine cancer. 

Enamine formation occurs by the thermolysis of diazo compounds (Scheme 150)67 109,278 284 288,304 332 453 454 via a carbene-like intermediate.284 332 When R1 = Ph, it enters into competition with hydrogen migration,284,332 and the electrophilic character of the carbene enhances the migration of the dimethylaminophenyl more than the phenyl.332 When triazoline synthesis is carried out at temperatures higher than that at which thermolysis of diazo compounds occurs, enamines are obtained exclusively, as in the addition of phenyl azide to cinnamic nitriles and ketones, with phenyl migration dominating in the nitrile.284 Enamine is also formed quantitatively in the reaction of ethyl diazoacetate with benzylideneaniline at 110°C.455... 

Treatment of 4-dimethylaminophenyl 4-RO-phenyl tellurium dibromides (R = CH3, C2H5, C6H5) with concentrated hydrochloric acid yielded the corresponding tellurium dichlorides6. 

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