Dimethyl sulfoxide sugar composition

Water is the only solvent in which the composition of sugars has been systematically explored. Stevens1674 has determined the composition of several aldoses in pyridine-d5 by -n.m.r, spectroscopy at 300 MHz. There are scattered data on solutions in organic solvents (mainly pyridine, dimethyl sulfoxide, and N,N-dimethylformamide), but only rarely have four (or more) components of such solutions been quantitatively determined. The data that have been encountered are collected in Table VII undoubtedly, there are others that have been missed. 

In dimethyl sulfoxide solution, some of the sugars have nearly the same composition as in aqueous solution. Others, particularly fructose, galactose, and talose, have very different compositions. There seems to be no obvious explanation for this behaviour (Angyal 1994). 

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