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1.3- Dimethyl-phenothiazines

Synonyms chloropromazine hydrochloride 2-chloro-N,N-dimethyl-ioH-phenothiazine-io-propanamine monohydrochloride 2-chloro-io-(3-dimethylaminopropyl)phenothiazine monohydrochloride chlorpromazine chloride chlorpromazinium chloride Phenothiazine hydrochloride Aminazin monohydrochloride Ampliactil monohydrochloride 4560 RP hydrochloride Propaphenin hydrochloride Largactil monohydrochloride Thorazine hydrochloride io-(3-dimethylaminopropyl)-2-chlorophenothiazine monohydrochloride 2-chloro-N,N-dimethyl-phenothiazine-io-propanamine monohydrochloride chloro-io-(3-dimethylaminopropyl)phe-nothiazine monohydrochloride... [Pg.1203]

As described In U.S. Patent 3,023,146, in a round-bottomed flask were placed 35 g of 2-propionyl phenothiazine (0.14 mol) 7 g of 50% sodium hydride in mineral oil (0.14 mol), and 240 cc of dimethyl formamide dried over sodium hydride. The resultant solution was stirred at room temperature for 2 hours, and then 88 g (0.56 mol) of trimethylene chlorobromide wes added at once. [Pg.255]

Chemical Name 2-chloro-N,N-dimethyl-10H-phenothiazine-10-propanamine hydrochloride Common Name N-(3-dimethylaminopropyl)-3-chlorophenothiazine... [Pg.321]

Chemical Name N,N-Dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl] -phenothiazine-2-sulfonamide... [Pg.1468]

Chemical Name N,N-Dimethyl-2-(trifluoromethyl)-1 OH-phenothiazine-10-propanamine Common Name Fluopromazine... [Pg.1540]

CN 10-[2-(dimethylamino)propyl]-V,V-dimethyl-10//-phenothiazine-2-sulfonamide mesylate... [Pg.669]

RN 13799-03-6 MF CnHnNOjS MW 315.39 EINECS 237-453-0 CN 7-methoxy-a,l 0-dimethyl-10//-phenothiazine-2-acetic acid... [Pg.1745]

The phenothiazines, chlorpromazine and promethazine, have been described as inhibitors of CCU-induced lipid peroxidation at relatively high concentrations in rat liver microsomes (Slater, 1968). Structural modifications of chlorpromazine were undertaken to try to increase antioxidant activity and maintain molecular lipophilicity. The 2-N-N-dimethyl ethanamine methanesulphonate-substituted phenothiazine (3) was found to be a potent inhibitor of iron-dependent lipid peroxidation. It was also found to block Cu -catalysed oxidation of LDL more effectively than probucol and to protect primary cultures of rat hippocampal neurons against hydrogen peroxide-induced toxicity in vitro (Yu et al., 1992). [Pg.271]

The thioxanthenes differ from the phenothiazines by the replacement of nitrogen in the central ring with a carbon-linked side chain fixed in space in a rigid structural configuration. An N,N-dimethyl sulfonamide functional... [Pg.199]

Experiments carried out by T. Urbanski, Szyc-Lewanska and Kalinowski [87] suggest the structure of 2,4-dinitro-3-(methyl)nitramino-7-(dimethyl)amino-5,5-dioxyphenothiazine (II) for the Gnehm product. The phenol produced by alkaline hydrolysis has the structure of 2,4-dinitro-3-hydroxy-7-(dimethyl)amino-5,5-dioxy-phenothiazine (III)... [Pg.74]

HI - 10H-PHENOTHIAZINE-2-ACETIC ACID, 7-METHOXY-alpha,10-DIMETHYL-,... [Pg.158]

Chemical Name 10H-Phenothiazine-2-sulfonamide, 10-(3-(4-(2-hydroxyethyl)-l-piperidinyl)propyl)-N,N-dimethyl-... [Pg.2770]

Chemical Name N,N-Dimethyl-10FI-phenothiazine-10-propanamine hydrochloride... [Pg.2868]

The number of different metabolic routes which are possible results in a complex mixture of metabolites for many phenothiazines. For example, many of the drugs which contain an AA-dimethyl-aminoalkyl side-chain (e.g. chlorpromazine) are extensively metabolised by A-oxidation, together with hydroxylation, sulphoxidation, and A-dealkylation. [Pg.288]

SYNS ACEPRONLAZINA ACEPROALAZINE ACEPROMIZINA ACETAZINE ACETHYL-PROMAZIN 3-ACETYL-lO (3-DIMETHYL-AMINOPROPYL)PHENOTHIAZINE ACETYL-PROMAZINE ANATRAN ANERGAN ATRAVET... [Pg.12]

DIETHYLAMINOETHYL-2-PHENYL-3-METHYLVALERATE METHYL BROMIDE see VBKOOO 5-P-DIETHYLAMINOETHYL-3-PHENYL-l,2,4-OXADIAZOLE CITRATE see OOEOOO 10-(2-DIETHYLAMINO-2-METHYLETHYL)PHENOTHIAZINE see DIROOO 2-DIETHYLAMINO-6-METHYLPYRIMIDIN-4-YL DIMETHYL PHOSPHOROTHIONATE see DIN800... [Pg.1625]

O, 0-DIMETHYL-0-(2,4,5-TRICHL0RPHENYL)-THIONOPHOSPHAT (GERMAN) see RMA500 N,N-DIMETHYL-2-(TiaFLUOROMETHYL)-10H-PHENOTHIAZINE-IO-PROPANAMINE see TKLOOO... [Pg.1649]

Davies AK, Navaratnam S, Phillips GO. Photochemistry of chlorpromazine (2-chloro-N-(3-dimethyl-aminopropyl) phenothiazine) in propan-2-ol solution. J Chem Soc Perkin Trans 1976 2 25-29. [Pg.222]

See other pages where 1.3- Dimethyl-phenothiazines is mentioned: [Pg.22]    [Pg.357]    [Pg.419]    [Pg.22]    [Pg.25]    [Pg.144]    [Pg.24]    [Pg.692]    [Pg.49]    [Pg.1305]    [Pg.307]    [Pg.445]    [Pg.1723]    [Pg.2109]    [Pg.1098]    [Pg.100]    [Pg.100]    [Pg.318]    [Pg.2869]    [Pg.291]    [Pg.2109]    [Pg.931]    [Pg.1046]    [Pg.526]   
See also in sourсe #XX -- [ Pg.210 ]



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