2.5- Dimethoxy aniline

Carbaryl UV Formulations Coupling/complexing with 2-amino-4-nitrophenol and 2,4-dimethoxy aniline detection in the 510-520 nm interval... 

The reaction of the tetrafluoroethylene trimer with aniline or 2,5-dimethoxy-aniline forms 2-trifluoromethyl-3-(l-N-phenylimino-2,2,2-trifluoroethyl)-4-(N-phenylamino)quinoline 113 (whose structure was confirmed by X-ray analysis) and 2-trifluoromethyl-3-pentafluoroethyl-4-(N-2,5-dimethoxyphe-nyl)-amino-5,8-dimethoxyquinoline 114 with yields 80 and 75%, respectively (98JFC(88)169). 

Even polyalkoxy-s-triazines are quite prone to nucleophilic substitution. For example, 2,4,6-trimethoxy-s-triazine (320) is rapidly hydrolyzed (20°, dilute aqueous alkali) to the anion of 4,6-dimethoxy-s-triazin-2(l )-one (331). This reaction is undoubtedly an /S jvr-4r2 reaction and not an aliphatic dealkylation. The latter type occurs with anilines at much higher temperatures (150-200°) and with chloride ion in the reaction of non-basified alcohols with cyanuric chloride at reflux temperatures. The reported dealkylation with methoxide has been shown to be hydrolysis by traces of water present. Several analogous dealkylations by alkoxide ion, reported without evidence for the formation of the dialkyl ether, are all associated with the high reactivity of the alkoxy compounds which ai e, in fact, hydrolyzed by usually tolerable traces of water. Brown ... 

T3 M 75.1% after 15 days 4-(6-Imino-2, 4-dimethoxy pyrimidin-l-yl) aniline additional metabolites were preliminary assigned but not confirmed [22]... 

If 3-methoxy-aniline is used, 6-methoxy-DET will probably result, but if 3,5-dimethoxyaniline is used, 4,6-dimethoxy-DET should be obtained. 

One of the carbazole-l,4-quinones, 3-methoxy-2-methylcarbazole-l,4-quinone (941), required for the total synthesis of carbazomycin G (269), was already used as a key intermediate for the total synthesis of carbazoquinocin C, and was obtained by the addition of aniline (839) to 2-methoxy-3-methyl-l,4-benzoquinone (939), followed by oxidative cyclization with catalytic amounts of palladium(II) acetate (545,645) (see Schemes 5.124 and 5.125). Similarly, in a two-pot operation, 4-meth-oxyaniline (984) was transformed to 3,6-dimethoxy-2-methylcarbazole-l,4-quinone... 

Bei der Reaktion von 4-Methoxy-anilin mit Natriumperjodat in neutraler, waBriger Losung bildet sich zu 25 30% 4,4 -Dimethoxy-azobenzol2. 

NO, Xr-ccHi OCHj H2/Raney-Ni/CH3OH 7000 kPa 40-70° 90 min 3-( Dimethoxy-methyl)-anilin 67-78 4... 

Die Kondensation von Cyclohexanon mit Diphenylamin unter Kalalyse durch Palladium-Kohlc bei 260° (12 h)ergibt Triphenylamin ( 72%). Die Umsetzung von 1.5-Dimcthyl-3-oxo-cyclohexenmit Ammoniak in Nitrobenzol/l,2-Dimethoxy-ethan in Gegenwart von Palladium auf Aluminiumoxid bei hoherer Tem-peratur unter Druck ergibt 3,5-Dimethyl-anilin (92%)J ... 

Alkoxy derivatives of biphenyl can be obtained either from alkoxy-anilines or by coupling with alkoxybenzenes. From diazotized p-bromo-aniline and anisole a 20% yield of 4-bromo-2 -methoxybiphenyl and a 7% yield of 4-bromo-4 -methoxybiphenyl are obtained. In connection with their studies on Cannabis Indica, Ghosh, Pascall, and Todd u prepared the highly substituted biphenyl compound, 2-cyano-5-methyl-2, 5 -dimethoxy-4 -n-amylbiphenyl (VII), in 27% yield from the nitrosoacetyl derivative of 2-cyano-5-methylaniline and 2,5-dimethoxy-n-amylben-zene. 

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