1 -Diisopropylamino-2-methyl

A -Diisopropylamino)methyl]-2-methyl-2ff-benzo[ ][l,2]thia-zine-l,l-(lioxide (15a)... 

General Procedure for Synthesis of (Aminomethyl)isoquino-line-Fused Polycyclic Compounds by Domino Mannich-Type Reaction and Cascade Cyclization Synthesis o/6-/(N,N-Diisopropylamino)methyl]-3,4-dihydro-2H-pyrimido[2,l-SL] isoquinoline (12a) (Table 1, Entry 10)... 

N, -Diisopropylamino)methyl]-9-Fluoro-3,4-Dihydro-2K-Pyrimido[2,l-Si]isoquinoline (12b)... 

Amination of 2,3-diiodo-5,6-dimethylbenzene-l,4-diol with i-PrNH2 gave 3,6-bis(isopropylamino)toluquinone as the only product (eq 26) Amination of the same substrate with n-BuNH2 afforded a mixture of 2,3-dimethyl-6-(n-butylamino)-l,4-benzoquinone and 3,6-bis(n-butylamino)-toluquinone (eq 21)P The latter was formed from the reaction of 2,3-dimethyl-6-(n-butylamino)-l,4-benzoquinone in refluxing w-BuNH2 in air in 100% yfleld (eq 29). A mixture of l-isopropyl-2,5,6-trimethylindole-4,7-quinone and 5,6-bis((diisopropylamino)methyl)-2,3-diiodohydroquinone was formed in the reaction with (i-Pr)2NH (eq 28). ... 

Diisopropylamino-a,a-diphenylbutyramide in propanol was refluxed 4 hours in the presence of excess methyl iodide. Upon dilution of the solution with ethyl acetate (100 ml per 50 ml isopropyl alcohol) and cooling 7-diisopropylamino-a,a-diphenylbutyramide methiodide precipitated, was collected by filtration and recrystallized (9.0 g) by dissolving in a hot mixture of 100 ml isopropyl alcohol and 10 ml methanol and then diluting with 90 ml Skellysolve B, to give B.3 g recrystallized product, MP 1B2° to 1B4°C. 

GTP was employed for the synthesis of block copolymers with the first block PDMAEMA and the second PDEAEMA, poly[2-(diisopropylamino)e-thyl methacrylate], PDIPAEMA or poly[2-(N-morpholino)ethyl methacrylate], PM EM A (Scheme 33) [87]. The reactions took place under an inert atmosphere in THF at room temperature with l-methoxy-l-trimethylsiloxy-2-methyl-1-propane, MTS, as the initiator and tetra-n-butyl ammonium bibenzoate, TBABB, as the catalyst. Little or no homopolymer contamination was evidenced by SEC analysis. Copolymers in high yields with controlled molecular weights and narrow molecular weight distributions were obtained in all cases. The micellar properties of these materials were studied in aqueous solutions. 

Phosphonothioic acid, methyl-, S-(2-bis(l-methylethylamino)ethyl) 0-ethyl ester O-ethyl S-(2-diisopropylaminoethyl) methylphosphonothiolate S-2-Diisopropylaminoethyl O-ethyl methylphosphonothioate S-2((2-Diisopropylamino)ethyl) O-ethyl methylphosphonothiolate O-ethyl S-(2-diisopropylaminoethyl) methylphosphonothioate O-ethyl S-(2-diisopropylaminoethyl) methylthiolphosphonoate S-(2-diisopropylaminoethyl) o-ethyl methyl phosphonothiolate Ethyl-S-dimethylaminoethyl methylphosphonothiolate VX EA 1701 TX60... 

Vacuum thermolysis (160°C) of the hemiaminal 11 generates the azaphos-phetane 65 in 85% yield.32 This product clearly results from the intramolecular insertion of the transient (amino) (phosphino)carbene 2h into the C-H bond of a diisopropylamino group bonded to phosphorus. Note that the four-membered heterocycle 65 is formed exclusively in spite of the ratio of six methyl-CH bonds to one methine-CH bond, and that only one of the two possible diastereomers is detected. The same regio- and diastereo-selectivity have already been observed with the di(phosphino)carbene 2g,74 but is in marked contrast to the exclusive formation of five-membered rings... 

Allylische Nitro-Verbindungen reagieren mit primaren und sekundaren aliphatischen Ami-nen in Acetonitril in Gegenwart von Palladium(0)-Komplexen unter Ersatz der Nitro-Gruppe durch eine Amino-Gruppe. Man erhalt so aus 4-Methyl-4-nitro-5-hexensaure-methylester und Diisopropylamin 6-Diisopropylamino-4-methyl-4-hexensdure-methylester (50%)... 

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