Dihydroxy-amino-octadecene

The major sphingosine base found in animal tissues is D-erythro-l, 3 dihydroxy-2 amino octadecene-4 or Chs sphingosine. This material is usually accompanied by small amounts of its saturated derivative, di-hydrosphingosine. Early studios designed to elucidate the pathway of sphingosine biosynthesis employed intraperitoneal administration of various carbon-14 labeled precursors in young rats (Zabin and -Mead, 1953,... 

Sphingolipids are lipids that contain sphingosine (trans-D-e/7f/zro-l,3-dihydroxy-2-amino-4-octadecene) or a related... 

Lipids which contain sphingosine (trans-D-erythro-l,3-dihydroxy-2-amino-4-octadecene) or a related amino alcohol are known as sphingolipids. The commonest phospholipid in this class is the phosphoryl-choline ester of an A -acylsphingosine (or ceramide) which is more commonly called sphingomyelin ... 

Sphingosine is a base with a technical name of D-erythro-1,3-dihydroxy-2-amino-4-/ra -octadecene. In gangliosides, the base forms an acid amide linkage between the amino group in position 2 of the base and the carboxyl group of the fatty acid. This complex of base and fatty acid is named ceramide. 

Sphingosine has been shown to be 2-amino-l,3-dihydroxy-4-[Pg.560]

The sphingosine base, according to available information, is identical with the normal l,3-dihydroxy-2-amino-4-octadecene and is present in the D-erythro-configuration. 

Sphingolipids contain sphingosine, an amino alcohol with a long unsaturated hydrocarbon chain (D-erythro-1,3-dihydroxy-2-amino-trans-4-octadecene) instead of glycerol ... 

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