Dihydrorhodamine, peroxynitrite

Dihydrorhodamine, peroxynitrite determination, 740, 741 5,6-Dihydrothymine, thymine hydroperoxides, 927, 928, 930... [Pg.1455]

Peroxynitrite (ONOO-) is a cytotoxic reactive species that is formed by the reaction of nitric oxide and superoxide. Methods for measuring the scavenging capacity of peroxynitrite usually depend on either the inhibition of tyrosine nitration or the inhibition of dihydrorhodamine 123 (DHR) oxidation to rhodamine 123 (MacDonalds-Wicks and... [Pg.282]

Santos MR and Mira L. 2004. Protection by flavonoids against the peroxynitrite-mediated oxidation of dihydrorhodamine. Free Radic Res 38(9) 1011-1018. [Pg.304]

Dihydrorhodamine 123 (DHR) and DCFH are widely used for the detection of peroxynitrite. Peroxynitrite oxidizes DHR and DCFH with efficiency equal to 38% and 44%, respectively... [Pg.971]

Analytical methods for ONOO related to the vascular system have been reviewed. Special attention is given to assays involving oxidation of dihydrorhodamine 123 (345) to yield the fluorescent product rhodamine 123 (346, equation 118), luminol (124) CL and nitrotyrosine formation. The reaction of peroxynitrite and carbon dioxide or bicarbonate... [Pg.740]

Crow JP (1997) DichlorodUiydrofluorescein and dihydrorhodamine 123 are sensitive indicators of peroxynitrite in vitro implications for intracellular measurement of reactive nitrogen and oxygen species. Nitric Oxide 1 145-157... [Pg.397]

Szabo C, Salzman AL, Ischiropoulos H. Peroxynitrite-mediated oxidation of dihydrorhodamine 123 occuis in early sc s of endotoxic and hemorrht c shock and ischemia-repeifusion injury. FEBS Lett 1995 372 229-32. [Pg.201]

Martin-Romero, F. J. Gutierrez-Martin, Y. Henao, F. Gutierrez-Merino, C. Fluorescence measurements of steady state peroxynitrite production upon SIN-1 decomposition NADH versus dihydrodichlorofluorescein and dihydrorhodamine 123. J. Fluoresc. 2004,14,17-23. [Pg.172]

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