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Dihalides tumor inhibition

Tumor Inhibition by Metallocene Dihalides of Early Transition Metals... [Pg.315]

To study the structure-activity relation of the metallocene dihalides, the influence of chemical variation upon the tumor-inhibiting activity was investigated. Principally, a metallocene dihalide molecule offers thfee different positions to be modified (Figure 1) (i) At the position of the central metal atom M, one... [Pg.316]

Modification of the Cyclopentadienyl Ligands, The results described so far suggest that the MX2 moiety within the metallocene dihalides represents the active center of the molecules. However, modification of the cyclopentadienyl rings in (C5H5)2TiCl2 as the model system also has a significant influence on the tumor-inhibiting potency of titanocene dichloride. [Pg.321]

See other pages where Dihalides tumor inhibition is mentioned: [Pg.315]    [Pg.315]    [Pg.316]    [Pg.321]    [Pg.324]    [Pg.798]    [Pg.304]    [Pg.325]   


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