2.6- diformyl-4-methylphenol

In contrast with the Schiff base salen, salicylaldehyde oxime (79) (salox) complexes of Co have received comparatively little attention, but a series of bis-bidentate divalent complexes of the form iraiis-Co(sa 1 ox)2( D M SO)2 have been reported.343 The heterocyclic bidentate oxime violurate (lH,3H-pyrimidine-2,4,5,6-tetrone 5-oximate, Hvi) (80) and its /V-methyl (mvi) and /V,/V -dimethyl (dmvi) derivatives form high-spin divalent [Co(vi)]+ and Co(vi)2 complexes, whereas [Co(vi)3] is low spin.344 The mixed-ligand Co(dmvi)2(phen) complex is also low spin. The crystal structure of m-Co(pxo)2Br2 (pxo = 2-acetylpyridine-l-oxide oxime) is isostructural with the Ni11 relative.345 The dichloro complex also adopts a cis configuration. The tridentate dioximes 2,6-diformyl-4-methylphenol dioxime and 2,6-diacetyl-4-methylphenol dioxime (Hdampo) form binuclear complexes of the type (81a) and (81b) respectively.346 Cobalt oxide nanoparticles were prepared by... 

Using 2,6-diformyl-4-methylphenol dioxime, Tasker, Schroder, and their co-workers conducted a magnetostructural study on complex (374) (pseudo macrocyclic structure Cu-Cu 2.994 A 2J= — 904 cm-1).330 Using 2-hydroxy-5-nitro-benzaldehyde benzoylhydrazone as ligand, complex (375) (Cu-Cu 3.041 A 2J=—372cm 1) was reported.331 Using 3-formylsalicylic acid oxime Okawa and co-workers reported complex (376) (square-planar and SP geometry Cu-Cu 2.961 A).332... 

Spontaneous formation of the Schiff base [3 + 6] macrocycle being a derivative of 2,6-diformyl-4-methylphenol and polyamine has been shown by Schmidt et al. [10].26... 

Scheme 7. Synthetic scheme for the asymmetric functionalisation of [9]aneN3 with different pendant donor groups starting from L11. z 2,6-diformyl-4-methylphenol, MeOH, reflux, 2 h z z NaBH4/NaBH3CN, MeOH, r.t., 30 h zzz tert-butylbromoacetate, CHC13, NEt(iPr)2, r.t., 12 h zv 2-bromoethanol, EtOH, K2CQ3, 50 °C, 16 h v HC1 0.01 M, r.t., 12 h.

Novel chiral Robson-type tetraimine macrocyclic complexes with Co(II), Co(III), Mn(II), and Mn(III) have been synthesized by metal template condensation of 2,6-diformyl-4-methylphenol with (l/f,2/f)-diaminocyclohexane or (lR,2R)-diphenyl-ethylenediamine. The dinuclear Co(II) and Co(III) complexes were shown to catalyse asymmetric cyclopropanation of styrene with diazoacetate cooperatively and with high enantioselectivity.118... 

Synthesis of Dinuclear and Tetranuclear Copper(ll) Complexes of 2,6-Diformyl-4-methylphenol-di(benzoylhydrazone) [256b]... 

To an ethanolic solution (35mL) of 2,6-diformyl-4-methylphenol (lmmol) was added ben-zoylhydrazide (2mmol) in ethanol (lOmL). To this solution was added one drop of concentrated HC1 and the mixture was heated at ca. 60°C for 1 hr and allowed to stand overnight. The precipitate was filtered off, washed with ethanol, and dried in air. Yield ca. 80%. 

The ground and excited state proton transfer processes of 4-methyl-2,6-diacetyl-phenol and the influence of polar solvents on the outcome of the photochemical transformation of 2,6-diformyl-4-methylphenol (10) has been evaluated" " . The results obtained from the study of 10 indicate that the CO- -HO hydrogen bond is stronger in... 

L = the macrocyclic 2 2 Schiff base condensation of 2,6-diformyl-4-methylphenol with N,N-bis(2-aminomethyl)methylamine. 

BCJ3337>. In this case, 2,6-diformyl-4-methylphenol is allowed to react with a diamine such as 1,3-diaminopropane. The imine formation reaction is templated by Pb(II) and formation of four bonds leading to the tetraimine occurred in 64% yield (Pb complex). In the strictest sense, this compound does not possess both O and N in the macroring, but both atoms are present in the... 

ICC1063) and di- 318 (02JCS(D)441) azine-coordinated nickel complexes can be prepared from pyridine-containing aldimines of 2,6-diformyl-4-methylphenol. A nickel cationic complex of a 2,6-bis-azomethine derivative contains two coordinated pyridine N-substituents 319 (M = Ni, R = H, R = Me, = MeOH) (96T3521). Zinc chelate 319 (M = Zn, R = R = Me, no L) has a similar structure (02IC6426). Tetranuclear manganese poly-chelate contains two coordinated pyridine... 

An extensive series of homo-bimetallic and hetero-bimetallic complexes of the 10-donor, doubly deprotonated ligand Hj-XXXI has been recently obtained (Guerriero et al. 1990). Both the direct complexation of the lanthanide salt(s) with the presynthesized ligand, in the presence of a base, and the metal-templated synthesis from 2,6-diformyl-4-methylphenol and l,8-diamino-3,5-dioxaoctane were found to be suitable for the preparation of the complexes. The homobinuclear complexes were obtained as homogeneous mierocrystals (5 10 pm thick platelets). The heterobi-nuelear eomplexes were microerystalline powders for which all evidence indicated. 

It is noteworthy that sodium 2,6-diformyl-4-methylphenolate reacts easily with 1,3-diaminopropane, leading to a 2 -t- 2 macrocycUc Schiff base isolated as its disodium complex [26]. The latter undergoes transmetallation by transition metals to yield dinuclear macrocyclic complexes [27]. 

LanthaDide(III) and yttriimi(III) ions have been reported to promote 2 + 2 condensation of 2,6-diformyl-4-methylphenol and a rigid 2,6-diaminopyridine ligson [68], Decreasing the metal ion radii of the lanthanide(III) cations diminishes the yield of the final product, whereas their potential ability to act as a template remains intact. 

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