9,10-Difluorostearic acid

Fluorinated acids and acid derivatives Fluorostearic acidic 9,10-Difluorostearic acid< Monofluoroundecanic acide Sodium monofluoroleate Methyl fluoroundecanate ... 

Langmuir isotherms report the relative conformational stability of )-erythro-and ( )-f/7reo-9,10-difluorostearic acids, J. Chem. Soc. Chem. Commun. (2002) 1226-1227. 

Reversing the order of addition, or using an ether as a solvent, causes a marked retardation of the reaction, with subsequent sudden, uncontrollable speed-up. Yields of about 80% are obtained and probably can be improved by devices to minimize the mechanical losses. 0 The addition of hydrogen fluoride to stearolic acid in methylene chloride solution to give 9,10-difluorostearic acid is cited in the patent literature.46 This claim should be verified, as either 9,9- or 10,10-difluoro-stearic acid or a mixture is much more likely to be the reaction product. 

Fig. 3 erythro- and r/ireo-9,10-difluorostearic acid 1 and 2 and Newman projections capturing their preferred conformations... 

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