Diffusion PFG NMR

Measurement of diffusion using pulsed field gradient NMR (PFG-NMR) is a powerful analytical tool because it combines the high specificity and information content of NMR spectroscopy with the size selectivity of diffusion coefficients. PFG-NMR employs timescales of tens of ms and has a displacement sensitivity of the order of 100 nm. PFG-NMR can determine molecular self-diffusion coefficients in liquid phases down to a lower limit of 10 " m s Due to the combination of experimental convenience and straightforward interpretation, PFG-NMR has become the method of choice for studying translational diffusion. PFG-NMR experiments have been reported using H, H, Li, C, F and other nuclei. The time A over which PFG-NMR measurements are possible is limited. 

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