Differin - Adapalene

Retin-A or Renova (tretinoin), Tazorac or Avage (tazarotene), Differin (adapalene) and any other retinoids such as retinol. 

R. Ruhl and H. Nau, Deteimination of adapalene (CD271/Differin ) and retinol in plasma and tissue by on-line solid-phase exti action and HPEC analysis , Chro-matographia 45 269-274 (1997). 

Adapalene Differin 0.1% cream 0.1% gel Apply a small amount once daily before bedtime Same as tretinoin but may be less severe... 

Adapalene (Differin) is a third-generation retinoid with comedolytic, kera-tolytic, and antiinflammatory activity, ft is available as 0.1% gel, cream, alcoholic solution, and pledgets. A 0.3% gel formulation is also available. 

Adapalene (Differin) is a derivative of naphthoic acid that resembles retinoic acid in structure and effects. It is applied as a 0.1% gel once daily. Unlike tretinoin, adapalene is photochemically stable and shows little decrease in efficacy when used in combination with benzoyl peroxide. Adapalene is less irritating than tretinoin and is most effective in patients with mild to moderate acnevulgaris. 

DIFFERIN Solution, containing adapalene, is used for the topical treatment of acne vulgaris. Each milliliter of DIFFERIN Solution contains adapalene 0.1% (1 mg) in... 

Topical treatment of acne vulgaris Adapalene Differin Carbomer 940/sodium hydroxide Aqueous... 

Adapalene. Adapalene (Differin) is a white to off-white powder that is soluble in tetrahydrofuran. sparingly. soluble in ethanol, and practically insoluble in water. Adapalene is applied as a 0.1%. solution or gel for the treatment of acne vulgaris. The eyes. lips, and mucous membranes should be avoided. 

Adapalene (6-[3-(l-adamantyl)-4-methoxyphenyl]-2-naphthoic acid, 6, DifFerin Calderma Laboratories)... 

Adapalene (differin), a derivative of naphthoic acid, is a synthetic retinoid-like compound that is available in solution, cream, and gel formulations for topical use. In addition to displaying typical retinoid effects, it also has anti-inflammatory properties. Adapalene has similar efficacy to tretinoin, but unlike tretinoin, it is stable in sunlight and tends to be less irritating. 

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