Diethylstilbestrol ovary

In contrast to the above results, DDE has been detected as a mutagen in cultured Chinese hamster ovary cells. The carcinogenic estrogen, diethylstilbestrol (DES), also is missed by all of the mutagenesis-based assays which may reflect the operation of another mechanism of cancer induction in the case of hormone induced cancers. It should be noted, however, that a... 

Congenital abnormalities of the fallopian tubes are also extremely rare. As in the ovaries, they present more likely a sequelae of torsion or an inflammatory process. Tubes may be partially atretic or hypoplastic and associated with uterine abnormalities such as rudimentary uterine horn or bicornuate uterus. In infertility patients exposed to diethylstilbestrol, short sacciflated or dilated fallopian tubes have been reported [21]. 

Tumorigenidty A clear cell adenocarcinoma of the ovary has been linked to early diethylstilbestrol exposure in utero in a 45-year-old woman her mother had taken diethylstilbestrol throughout the pregnancy [7 ]. 

Dasanu CA, Herzog TJ. Clear cell adenocarcinoma of the ovary associated with in utero diethylstilbestrol exposure case report and clinical overview. Medscape J Med 2009 11(1) 6. 

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