Diethylstilbestrol -induced tumor

Dunning and colleagues244 reported that AXC female rats fed a purified diet containing 25% tryptophan-free casein hydrolysate plus 1.4% DL-tryptophan compared to those fed a 26% casein diet had an increase in the number (79 vs. 51) and percentage (100 vs. 75%) of induced mammary cancers, as well as a reduction in the average latent period (316 vs. 363 days). Tumors were induced by the implantation of cholesterol pellets containing 4 to 6 mg of diethylstilbestrol subcutaneously in the scapular region. However, rats fed... 

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