Dicyclohexylcarbodiimide insertion reactions

Insertion reactions of dicyclohexylcarbodiimide with amino-boranes, -boryls and -borylenes [92] ... 

Pierce GA, Coombs ND, Willock DJ, Day JK, Stasch A, Aldridge S (2007) Insertion reactions of dicyclohexylcarbodiimide with amino-boranes, -boryls and -borylenes. Dalton Trans, p 4405... 

Westerhausen and coworkers have reported the stoichiometric insertion reactions of [Ca(PPh2)2(THF)4] with 1,3-dicyclohexylcarbodiimide and 1,3-di-iso-propylcarbodiimide to yield homoleptic phosphaguanidinate complexes of... 

Alkali metal derivatives of 2-(trimethylsilyl)aminopyridines can be further derivatized by insertion of 1,3-dicyclohexylcarbodiimide. Functionalized guani-dinates are formed in this reaction via a 1,3-silyl shift. Scheme 170 illustrates the reaction sequence as well as the preparation of an aluminum complex of the modified ligand, which exhibits pseudo jS-diketiminate binding of the metal center, thus exemplifying the coordinative versatility of this new multi-N-donor system. ... 

This carbon-carbon bond-generating reaction can be used extensively over a wide range of chemistries [11]. As the reaction is an equilibrium process, needing the removal of water to obtain high yields, chemical means have to be used to accomplish this task. 1,3-Dicyclohexylcarbodiimide (DCC) is a commonly used reagent for this purpose. Alternatively, molecular sieves find use for conventional processing, but are not so favorable for micro-reactor processing, because the sieve needs to be inserted into the micro channel (additional fabrication expenditure) and may disrupt the liquid transport if EOF is applied. 

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