Methotrexate Dicloxacillin

Clinically important, potentially hazardous interactions with acitretin, aluminum hydroxide, amoxicillin, ampicillin, antacids, bacampicillin, betamethasone, bismuth, bromelain, calcium, carbenicillin, cholestyramine, doxacillin, corticosteroids, dairy products, dicloxacillin, didanosine, digoxin, food, glidazide, iron, isotretinoin, methicillin, methotrexate, methoxyflurane, mezlocillin, nafcillin, oxacillin, penicillins, piperacillin, retinoids, rocuronium, strontium ranelate, sucralfate, ticarcillin, vitamin A, zinc... 

Transporter absorptive effects predominant Examples. Acyclovir, Amiloride -, Amoxicillin Atenolol Atropine, Bidisomide Bisphosphonates Captoprit, Cefazolin Cetirizine Cimetidine Ciprofloxacin, Cloxacillin Dicloxacillin Erythromycin - -, Famotidine Fexofenadine Folinic acid Furosemide, Ganciclovir Hydrochlorothiazide, Lisinopril Metformin Methotrexate, Nadolol Penicillins Pravastatin Ranitidine Tetracycline Trimethoprim Valsartan Zalcitabine... 

Reduced clearance and acute methotrexate toxicity has been attributed to the concurrent use of various penicillins (amoxicillin, benzylpenicillin, carbenicillin, dicloxacillin, flucloxacillin, mezlocillin, oxacillin, penicillin, phenoxymethylpenicillin, piperacillin, ticarcillin) in a small number of case reports. 

Intravenous bolus 15 to 60 mg/m s then 15 to 60 mg/m intravenous infusion over 36 hours Dicloxacillin (not stated) (Indometacin ako given) Oesophageal cancer (1) 93% reduction in methotrexate clearance prolonged folinic acid rescue necessary 3... 

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See also in sourсe #XX -- [ ]

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