1.1- dichloro-2,3-dihydro

DICHLORODIHEXYLSTANNANE see DFC200 6,8-DICHLORO-DIHYDRO-l,3-BENZOXAZINE-2-THIONE-4-ONE see DFC300 (2,5-DICHLORO-3,6-DIHYDROXY-p-BENZOQUINOLATO)MERCURY see DFC800... 

Dichloro-, dihydro-, and hydrido-chloro-complexes [PtX2(PR3)2], [PtHX(PR3)2], and[PtH2(PRs)2] [X = Cl,Br,orI R3 = Pr 3,(cyclo-C6Hu)3,or(cyclo-C6Hu)2Ph] have been prepared and their spectral properties reported. ... 

Biphenyl)-4,4 -diamine, 3,3 -dichloro-, dihydro-chloride. AI3-22046 Benzidine, 3,j-dichloto-, dihydrochloride (1,T-Biphenyl)-4,4 -diamine, 3,3 -dichloro-, dihydro-chloride CCRIS 5899 3,3 -Dichlorobenzidine dihydrochloride EINECS 210-323-0 HSDB 5715 NSC 3524. 

In some instances a carbon-carbon bond can be formed with C-nucleophiles. For example, 3-carboxamido-6-methylpyridazine is produced from 3-iodo-6-methylpyridazine by treatment with potassium cyanide in aqueous ethanol and l,3-dimethyl-6-oxo-l,6-dihydro-pyridazine-4-carboxylic acid from 4-chloro-l,3-dimethylpyridazin-6-(lH)-one by reaction with a mixture of cuprous chloride and potassium cyanide. Chloro-substituted pyridazines react with Grignard reagents. For example, 3,4,6-trichloropyridazine reacts with f-butyl-magnesium chloride to give 4-t-butyl-3,5,6-trichloro-l,4-dihydropyridazine (120) and 4,5-di-t-butyl-3,6-dichloro-l,4-dihydropyridazine (121) and both are converted into 4-t-butyl-3,6-dichloropyridazine (122 Scheme 38). 

Imidazole, 4,5-dibromo-l-methyl-synthesis, S, 399 Imidazole, 4,5-di-t-butyl-synthesis, S, 483 X-ray diffraction, S, 350 Imidazole, 4,5-dichloro-chlorination, S, 398 synthesis, S, 398, 473 Imidazole, 4-(3,4-dichlorophenyl)-nitration, 5, 433 Imidazole, 4,5-dicyano-hydrolysis, S, 435-436 synthesis, S, 461, 472, 487 Imidazole, 4,5-dicyano-1-vinyl-synthesis, S, 387 Imidazole, 4,5-dihydro-mass spectra, 5, 360 Imidazole, 4-(dihydroxybutyl)-synthesis, S, 484 Imidazole, 4,5-diiodo-nitration, S, 396 synthesis, S, 400 Imidazole, 2,4-diiodo-5-methyl-iodination, S, 400 Imidazole, 1,2-dimethyl-anions... 

Indole, 3-(dialkylaminomethyl-) alkylation, 4, 275 Indole, 2,3-dibromo-synthesis, 4, 215 Indole, 2,6-dibromo-3-methyl-synthesis, 4, 215 Indole, 1,3-dichloro-synthesis, 4, 214 Indole, dihydrodehydrogenation, 4, 283, 311 in non-silver photography, 1, 383 Indole, 2,3-dihydro-synthesis, 4, 327, 352 Indole, 2,3-dihydroxy-tautomerism, 4, 37, 199 Indole, 4,6-dimethoxy-... 

Isothiazole, 3,5-dichloro-4-cyano-synthesis, 6, 166 Isothiazole, dihydro-1,1-dioxide... 

Lumazine, 6,7-dichloro-l,3-dimethyl-reactions, 3, 292 Lumazine, 7,8-dihydro-... 

Pteridine, 4,7-dichloro-2-methylthio-synthesis, 3, 296 Pteridine, 3,4-dihydro-structure, 3, 279 Pteridine, 5,6-dihydro-properties, 3, 306 Pteridine, 5,8-dihydro-structure, 3, 306 Pteridine, 7,8-dihydro-... 

Pyrazine, 1,4-dialkyl-1,4-dihydro-isomerization, 3, 178 Pyrazine, dichloro-synthesis, 3, 187 Pyrazine, 2,3-dichloro-oxidation, 3, 169... 

Pyrazine, 2,5-dichloro-3,6-difluoro-synthesis, 3, 190-191 Pyrazine, dihydro-, 3, 177 Pyrazine, 1,2-dihydro-oxidation, 3, 178 reduction, 3, 177 Pyrazine, 1,4-dihydro-antiaromaticity, 3, 177-178 synthesis, 3, 177 Pyrazine, 2,3-dihydro-oxidation, 3, 178 Pyrazine, 2,5-dihydro-synthesis, 3, 178 Pyrazine, 3,6-dihydro-synthesis, 3, 184 Pyrazine, 2,5-dihydroxy-oxidation, 3, 175 Pyrazine, 2,3-dimethyl-1,4-dioxide... 

Pyridin-4-one, 3,5-dichloro-2,6-dimethyl-tautomerism, 2, 111 Pyridin-4-one, 1,4-dihydro-polymers, 1, 297 Pyridin-4-one, 2-dimethylamino-synthesis, 2, 419... 

Selenophene, 2,5-diamino-3,4-dicyano-synthesis, 4, 119, 964 Selenophene, 2,4-diaryl-synthesis, 4, 967 UV spectra, 4, 941 Selenophene, 2,5-diaryl-synthesis, 4, 967, 969 UV spectra, 4, 941 Selenophene, 2,5-dichloro-metallation, 4, 949 Selenophene, dihydro-3-methylene-synthesis, 4, 963 Selenophene, 2,5-dimethoxy-lithiation, 4, 949 Selenophene, 2,4-dimethyl-... 

We are the first group to succeed with the highly enantioselective 1,3-dipolar cycloadditions of nitronates [75]. Thus, the reaction of 5,6-dihydro-4H-l,2-oxazine N-oxide as a cyclic nitronate to 3-acryloyl-2-oxazilidinone, at -40 °C in dichloro-methane in the presence of MS 4 A and l ,J -DBFOX/Ph-Ni(II) complexes, gave a diastereomeric mixture of perhydroisoxazolo[2,3-fe][l,2]oxazines as the ring-fused isoxazolidines in high yields. The J ,J -DBFOX/Ph aqua complex prepared from... 

A mixture of 5.7 grams (0.02 mol) of 5-chloro-2,4-disulfamylaniline and 4.9 grams (0.04 mol) of dichloroacetaldehyde in 25 ml of dimethyl formamide was heated at the boiling temperature and under reflux for 30 minutes. The reaction mixture was thereafter poured into a mixture of ice and water to precipitate the desired 6-chloro-7-sulfamyl-3-dichloro-methyl-3,4-dihydro-1,2,4-benzothiadiazine-1,1-dioxide as a crystalline solid melting at 250° to 270°C with decomposition. 

Dichloro- and l,2-dibromo-l,2-dihydro-3-benzoxepins are dehalogenated with zinc in methanol to give 3-benzoxepin (6a) in excellent yield.93 A methoxycarbonyl group in the 2-position, however, diminishes the yield of 6b considerably.91... 

Benzoxepin undergoes addition of bromine and chlorine to give l,2-dibromo-l,2-dihydro-3-benzoxepin (2 a) and 1,2-dichloro-l, 2-dihydro-3-benzoxepin (2b), respectively.93 The bromination reaction of dimethyl 3-benzoxepin-2,4-dicarboxylate takes the same course to give 2c.91... 

Starting material 2.5-dichloro-4,5-dihydro-l-benzothiepin, b Overall yield from corresponding ketone (see Section 2.1.3.1). 

A solution of 2,4-dichloro-2,.3-dihydro-1-benzothiepin (0.5 g, 2.16 mmol) in f-BuOH (14 mL) was added in one portion to a solution of f-BuOK (246 mg, 2.20 mmol) in t-BuOH (24 mL). After stirring for 50 min, the turbid orange solution was poured into H20 (150mL) and extracted with CHCl3. The extract was washed with H20 and dried (MgS04). The solvent was removed under reduced pressure to give a yellow oil [yield 330 mg (79%)] which was further purified by chromatography (alumina, petroleum ether). 

Dehydrogenation is a rarely used method for the production of fully unsaturated azepines, and there are no examples of its use for the formation of simple monocyclic systems, although 3-hydroxy- and 3-methoxy-2//-azepin-2-ones can be obtained by dehydrogenation of the corresponding l,5-dihydro-2//-azepin-2-ones with 2,3-dichloro-5,6-dicyano-l,4-benzoquinone (DDQ) in benzene in a sealed tube at 100 48-51-52-67... 

On heating, the dichlorooxazolo[3,4- ]azepine 26, for which dimerization is prevented by the chloro groups, undergoes ring contraction and aromatization, involving a [l,2]-chlorine shift, to 5,8-dichloro-l,4-dihydro-2//-3,l-benzoxazin-2-one (27).11,153... 

Pyran, 3,4-dihydro-, 55, 63 Pyran, tetrahydro-, 2,3-dichIoro- [2//-Pyran, tetrahydro-, 2,3-dichloro-], 55, 63 Pyran, tetrahydro-, 3-chloro-2-methyl- [2H-Pyran, tetrahydro-, 3-chloro-2-methyl-], 55 63... 

Sulphines may react as dienophiles with 1,3-dienes with the formation of cyclic sulphoxides. Unstable 2,2-dichloro-5,6-dihydro-2ff-thiin-l-oxide 191 was formed in an exothermic reaction between 173aandcyclopentadieneat — 40 (equation 101). The simplest, parent sulphine, CH2 = S = O, prepared in situ by treatment of a-trimethylsilylmethanesulphinyl chloride with cesium fluoride, reacts with cyclopentadiene to give bicyclic, unsaturated sulphoxide 192 as a mixture of two diastereoisomers in a 9 1 ratio (equation 102). On the other hand, a,j8-unsaturated sulphine 193 (generated by thermolysis of 2-benzylidene-l-thiotetralone dimer S-oxide) in boiling toluene behaves as a 1,3-diene and was trapped by norborene forming sulphoxide 194 in 78% yield ° (equation 103). 

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