2.6- Dichloro benzoic acid

Pentachlorobenzoic acid has been prepared by oxidation of pentachlorotoluene with nitric acid and mercury, by oxidation of pentachlorobenzaldehyde by potassium permanganate,6 and by chlorination of tetrachlorophthalyl chloride 6 and of dichloro-benzoic acids.7 Pentachlorobenzoic acid recently has been prepared by the exhaustive chlorination of benzoic acid in sulfuric acid containing iodine.8 The present procedure has been adapted from that of Pearson, Cowan, and Beckler.9... 

Soil. The major soil metabolite is 2,6-dichlorobenzamide which degrades to 2,6-dichloro-benzoic acid. The estimated half-lives ranged from 1 to 12 months (Hartley and Kidd, 1987). Under field conditions, dichlobenil persists from 2 to 12 months (Ashton and Monaco, 1991). The disappearance of dichlobenil from a hydrosol and pond water was primarily due to volatilization and biodegradation. The times required for 50 and 90% dissipation of the herbicide from a hydrosol were approximately 20 and 50 d, respectively (Rice et al., 1974). Dichlobenil has a high vapor pressure and volatilization should be an important process. Williams and Eagle (1979) found... 

Dichloro benzoic acid didobutrazol, hexaconazole, penconazole, pyrifenox... 

It is interesting that ndther derivatives hydroxylated on the rit, nor 3,5-dichloro-benzoic acid, were found as end-products of metabolism. 

Dichloro benzoic acid Double electron-electron resonance Experimental diffusion coefficient... 

Fig. 67 Models of (a) the calcite(10.4) surface and (b) organic molecules 4-iodo benzoic acid (IBA), 2,5-diiodo benzoic acid (DIBA), 2,5-dichloro benzoic acid (DCBA), 3,5-diiodo salicylic acid (DISA) and 2-(4-bromophenyI)-6-(4-chIorophenyl)pyridine-4-carboxyIic acid (BPCPPCA). The CaC03 (10.4) surface has a rectangular unit cell of size 0.50 x 0.81 nm, consisting of two carbonate groups and two calcium ions. The carbonate groups are rotated such that one oxygen atom lies above, one in, and one below the plane spanned by the calcium ions...

Comparison of the ultraviolet spectra of different dichloro benzoic acids clearly showed this effect to be operating. The orfAo-substituents should not be larger than Cl or CH3, as 2,6-dibromobenzoic acid is inactive. 

Benzoic acid-3,6-dichloro-2-methoxy-2-ethoxy-l-methyl-2-oxoethyl ester [87214-73-1]... 

Chemical Name 2-((2,6-Dichloro-3-methylphenyl)emino] benzoic acid ethoxymethyl ester Common Name Etoclofene Structural Formula ... 

CN 2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid tnonosodium salt... 

Zhao H, Jaynes WF, Vance GF (1996) Sorption of the ionizable organic compound, dicamba (3,6-dichloro-2-methoxy benzoic acid), by organoclays. Chemosphere 33 2089-2100... 

In a series of ten morphine 3-benzoates, large differences in rates of enzymatic hydrolysis were seen [122], In 80% human plasma at pH 7.4 and 37°, the unsubstituted 3-benzoate had a tm value of 0.6 h, whereas esters of 2,6-disubstituted benzoic acid were much more resistant to enzymatic attack (t1/2 ranging from 60 h for the dimethylbenzoate to 300 h for the dichloro-and dimethoxybenzoates). Although these results point to marked steric hindrance, electronic effects cannot be excluded but escape characterization because of the limited series. Furthermore, and as mentioned repeatedly in this text, the possibility of binding to plasma proteins is a complicating factor that should be kept in mind. 

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