Dicaffeoyltartaric acid

The red-leaved lettuce Lollo Rosso contains the hydroxycinammates caf-feoyltartaric acid, dicaffeoyltartaric acid, 5-O-caffeoylquinic acid, and 3,5-0-dicaffeoylquinic acid (Fig. 1.31) [Ferreres et al., 1997]. 5-O-Caffeoylquinic acid has also been detected in tomatoes [Paganga et al., 1999]. 

Tartaric acid Feruloyl (i.e., ferulic acid) 2,3-O-dicaffeoyltartaric acid (Cichoric Acid) R1, R2 = X 2-0-caffeoyl-3-0-feruloyltartaric acid R1 = X, R2 = Y 2-O-caffeoyltartaric acid (Caftaric acid) R1 = X, R2= H... 

King, P., Ma, G., Miao, W., Jia, Q., McDougall, B., Reinecke, M., Cornell, C., Kuan, J., Kim, T., and Robinson, W. 1999. Structure-activity relationships analogues of the dicaffeoylquinic and dicaffeoyltartaric acids as potent inhibitors of human immunodeficiency virus type 1 integrase and replication. J. Med. Chem. 42, 497-509. 

Fig. (8). HPLC chromatogram of red lettuce anthocyanins and other phenols (1) caffeoyltartaric acid, (2) chlorogenic acid, (3) dicaffeoyltartaric acid, (4) quercetin 7-glucoside 3-(6 -malonylglucoside), (5) dicaffeoylquinic acid dsochlorogenic acid), (6) quercetin 3-glucuronido, (7) quercetin 3-glucosido, (8) quercetin 3-malonylglucoside, and (9) cyanidin 3-malonylglucoside. HPLC conditions RP Cjg column (12 x 0.4 cm particle size 5 pm). Mobile phase acidified water (5% formic acid) (A) and methanol (B). Gradient 0 min- 5% B, 25 min- 40% B. Flow rate I mL/min.

Scarpati ML, Oriente G (1958) Chicoric acid (dicaffeoyltartaric acid) Its isolation from chicory (Cichorium intybus) and synthesis. Tetrahedron 4 43-48... 

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