1-2-Dibromoethane

HUMAN CARCINOGEN, HARMFUL VAPOR, TOXIC IN CONTACT WITH SKIN 

Colorless liquid with sweetish chloroform-like odor bp, 131-132T.1 

Soluble in 250 parts water miscible with alcohol and ether.1 

Magnesium. Reaction to give Grignard compounds may be violent.2 

The vapor irritates the respiratory system and eyes. Liquid irritates the eyes and skin. Swallowing or skin absorption results in nausea, vomiting, and liver and kidney damage.3 Avoid breathing vapor. Avoid contact with skin and eyes.3 Animal carcinogen reasonably anticipated to be a human carcinogen.4 TLV, no exposure permitted.5 

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Bromine is used in the manufacture of many important organic compounds including 1,2-dibromoethane (ethylene dibromide), added to petrol to prevent lead deposition which occurs by decomposition of the anti-knock —lead tetraethyl bromomethane (methyl bromide), a fumigating agent, and several compounds used to reduce flammability of polyester plastics and epoxide resins. Silver(I) bromide is used extensively in the photographic industry... 

DibrOmoethane dibromide. Also has a very high Constant, but sometimes causes association of the solute. It usually gh es excellent consistent results. 

The flask was charged with 48 g of magnesium and 200 ml of dry diethyl ether. 1,2-Dibromoethane (4 ml) was added. After a few minutes a vigorous reaction started and the diethyl ether began to reflux. When this reaction had subsided, 500 ml of dry diethyl ether were added. Stirring was started and 1.0 mol of chlorocyclohexane (note 1) was added from the dropping funnel at a rate such that the diethyl ether gently refluxed (note 2). After this addition, which was carried out in 1 h, the flask was heated under reflux for a further 1 h. 

In 1881, Will (97) obtained 2-phenylamino-N-phenylthiazolidine (56) by condensing 1,2-dibromoethane with N,W -diphenylthiourea. 

Step 2 IS the conversion of the bromonium ion to 1 2 dibromoethane by reaction with bromide ion (Br )... 

The double titration method, which involves the use of ben2ylchloride, 1,2-dibromoethane, or aUyl bromide, determines carbon-bound lithium indirectly (101,102). One sample of the //-butyUithium is hydroly2ed directly, and the resulting alkalinity is determined. A second sample is treated with ben2ylchloride and is then hydroly2ed and titrated with acid. The second value (free base) is subtracted from the first (total base) to give a measure of the actual carbon-bound lithium present (active base). 

Quaternary Salts. Herbicides paraquat (20) and diquat (59) are the quaternary salts of 4,4 -bipyridine (19) and 2,2 -bipyridine with methyl chloride and 1,2-dibromoethane, respectively. Higher alkylpyridinium salts are used in the textile industry as dye ancillaries and spin bath additives. The higher alkylpyridinium salt, hexadecylpytidinium chloride [123-03-5] (67) (cetylpyridinium chloride) is a topical antiseptic. Amprolium (62), a quaternary salt of a-picohne (2), is a coccidiostat. Bisaryl salts of butylpyridinium bromide (or its lower 1-alkyl homologues) with aluminum chloride have been used as battery electrolytes (84), in aluminum electroplating baths (85), as Friedel-Crafts catalysts (86), and for the formylation of toluene by carbon monoxide (87) (see QuaternaryAA ONiUM compounds). 

Amino and sulfur analogues of pyrazolones also yield the aromatic quaternary salt (231 X = NH or S). If the pyrazole bears a substituent with a second pyridine-like nitrogen atom, an intramolecular bridge can be formed by reaction with a dihalogenoalkane. Thus pyrazol-I -ylpyridines react with 1,2-dibromoethane to form (233) (81JHC9). 

Ethylene dibromide (1,2-dibromoethane) Ethylene dichloride (1,2-dichloroethane) Ethylene glycol monomethyl ether acetate, see Methyl cellosolve acetate Ethylene oxide... 

Dibromoethane (ethylene dibromide) 2-Dibutylaminoethanol (aminoethanol compounds) Dibutyl phosphate... 

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