Diagnosis, safety assessment

Lindon J C, Holmes E, Bollard M E, et al. (2004). Metabonomics technologies and their applications in physiological monitoring, drug safety assessment and disease diagnosis. Biomarkers. 9 1-31. 

Measurement issues cut across many of the themes identified in this chapter and are an important priority for the future. Recent work by the Health Foundation in the UK following the publication of the Francis report (Francis 2013) has underlined the importance of accurate diagnosis and assessment of quahty and safety in healthcare our ability to measure and assess quality of care is improving, [however]. .. there are still many aspects of care, and care services, for which routinely available information on quality is inadequate or nonexistent . (Health Foundation 2013 6)... 

R 423 J.C. Lindon, E. Holmes, M.E. Bollard, E.G. Stanley and J.K. Nicholson, Metabonomics Technologies and Their Applications in Physiological Monitoring, Drug Safety Assessment and Disease Diagnosis , Biomarkers, 2004,9,1... 

Zio, E. Popescu, I.C. 2006a. Fault Diagnosis of Nuclear Components by Kohonen Self-Organizing Maps. Proceedings of the Ei th International Conference on Probabilistic Safety Assessment Management (PSAM). 

Another approach uses a synthesis of RCTs and naturalistic studies, while addressing the limitations of both (Simon et al, 1995b Hotopf et al, 1996). In such studies the treatment setting is routine primary-care clinical practice selection criteria are limited to those affecting safety and treatment is normal , i.e. provided under conditions where differences in clinical practice and patient behaviour can emerge freely. However, participants are randomized to initial treatment, and accurate diagnosis and baseline assessments are recorded. This approach is... 

Most organisational safety culture assessments are not carried out for their own sake. Management is either interested in a diagnosis to compare it with a previous one or to benchmark with peer organisations, or the diagnosis is followed by... 

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