Diabetes alcoholism and

No population has been identified which is unusually susceptible to toxic effects resulting from -hexane exposure. It is possible that individuals with diminished peripheral nerve function may be more susceptible to w-hcxanc neurotoxicity than the general population. This group would include diabetics, alcoholics and the aged. 

Diabetes, alcoholism, and glucose 6-phosphatase deficiency all can produce less severe hypertriglyceridemia with an increase in VLDL and chylomicrons. Factors contributing to the hyperlipidemia are ... 

Pyridoxine, vitamin B6, (10-50 mg/day) is coadministered with isoniazid to minimize the risk of peripheral neuropathy and central nervous system (CNS) toxicity in malnourished patients and those predisposed to neuropathy (e.g., slow acetylators, elderly, pregnant women, human immunodeficiency virus [HrV]-infected subjects, diabetics, alcoholics, and uremics). 

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