Dextran hydrogels prepared

Zhang R. Dextran Hydrogel Preparation and Application in Biomedical Engineering. PhD Thesis, University of Bath, England, 2004. 

Dextran hydrogels, cross-linked by diisocyanate, released drug only in the distal part of the colon, where the conditions for absorption are not as conducive as in the proximal part [96], The pH-sensitive dextran hydrogels were prepared by activation... 

Hydrogels prepared via homogeneous esterification of dextran with unsaturated carboxylic acids are advanced polysaccharide-based products useful for drug delivery systems and protective encapsulants, e.g. of viruses used in gene therapy [173]. Very promising in this regard is the dextran maleic acid monoester [174], which can be obtained by conversion of dextran in DMF/LiCl with the maleic anhydride in the presence of TEA. The DS of the products can be easily controlled with the amount of anhydride applied but... 

Also aiming at biomedical applications are nanoscaled hydrogels, prepared in inverse miniemulsion. In crosslinked poly(oligo(ethylene glycol) monomethyl ether methacrylate) (POEOMA) nanogels hydrophilic dyes as the polymeric dye (rhodamine isothiocyanate (RITC) dextran) [41], rhodamine in combination with the drug doxorubicin [42] or gold nanoparticles with bovine serum albumin [43] could be encapsulated. 

Dextran is a biocompatible polymer used for the preparation of hydrogels. Dextran hydrogels can be obtained by several different approaches and they have received increased attention due to the variety of their biotechnological and biomedical applications. Dextran hydrogels have been frequently considered as a potential matrix system for colon-specific dehvery and/or controlled release (CR) of bioactive... 

Schacht, E., Bogdanov, B., Van Den Bulcke, A., and De Rooze, N. (1997) Hydrogels Prepared by Cross-Linking of Gelatin with Dextran Dialdehyde. React. Fund Polym., 33, 109-116. 

Hui Zhang, Hong Wu, Li Fan, Fei Li, Chun-hu Gu Min Jia (2009). Preparation and characteristics of pH-sensitive derivated dextran hydrogel nanoparticles, early view. D01 10.1002/pc.20684. 

A hydrogel with high sensitivity was prepared with chitosan (DA = 0.18) and dextran sulfate the maximum volume of the complex gel was observed in a dilute NaOH solution at pH 10.5, and was about 300 times as large as the volume at pH values below 9 [106,107]. 

Three-dimensional hybrid hydrogel networks were also prepared by the authors in the current application by functionalizing the step 5 derivatives with metha-cryloyl dextran. 

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