Detection lectin-gold probes

Rohnnger, R. and Holden, D W (1985) Protein blotting detection of protein with colloidal gold, and of glycoproteins and lectins with biotin-conjugated and enzyme probes Anal Biochem. 144, 118-127. 

Lectins, or proteins with specific binding sites for carbohydrates, can be used as targeting molecules to localize particular glycoconjugates such as glycoproteins or glycolipids on cell surfaces (Fig. 373). Labeled with gold particles, lectins are important probes for detection of cell surface components and intracellular receptors and in immunological or biochemical assay procedures (Bog-Hansen et al., 1978 Kimura et al., 1979 Nicolson, 1978 Roth, 1983 Benhamou et al., 1988 Nakajima et al., 1988). 

Rohringer, R., and Holden, D. (1985). Protein Blotting Detection of Proteins with Colloidal Gold, and of Glycoproteins and Lectins with Biotin-conjugated and Enzyme Probes, Anal. Biochem. 144 118-127. 

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