Desolvating microconcentric nebulizers

Martin, M., and Volmer, D. A. (1999). Examining the analytical capabilities of a desolvating microconcentric nebulizer for inductively coupled plasma-mass spectrometry. Rapid Commun. Mass Spectrom. 13(1), 84. 

In ICP-MS mostly liquids are analyzed. The aqueous solution is nebulized using an effective pneumatic nebulizer (e.g., Meinhard or MicroMist nebulizer with cyclonic spray chamber, ultrasonic nebulizer (USN), microconcentric nebulizer with desolvator (e.g., Aridus or APEX), the latter for the introduction of small volumes of solution)3 as described in Section 5.1.6. 

A frequently used micronebulizer with heated spray chamber and membrane desolvator is the Aridus from CETAC Technologies, Ohama, NE. The experimental setup of the Aridus II microconcentric nebulizer is shown in Figure 5.16. 

V.V-dicthyl-V -bcnzoy I thiourea (DEBT). The palladium complex formed was eluted with methanol and introduced into an ICP-SFMS via microconcentric nebulization with membrane desolvation. Isotope dilution analysis was employed for quantification purposes.80... 

ICP-MS is a multi-element technique suitable for the analysis of liquid samples, which provides higher selectivity and detection power and LoDs lower than other multi-element techniques, such as ICP-AES. These characteristics make ICP-MS an excellent tool for the detailed characterization of the elemental composition of beverages. In this context, ICP-MS was the technique selected for the determination of 31 trace elements in wine at concentrations ranging from 0.1 to 0.5 ng ml-1 [82]. Samples were diluted 1 + 1 and it was investigated whether a matrix effect derived from the presence of ethanol could be overcome by using a microconcentric nebulizer with membrane desolvation. The authors compared their results with those obtained using a conventional Meinhard nebulizer and concluded that the matrix effect observed could only be minimized by using an internal standard with the Meinhard nebulizer, but not with the other one. 

A suitable calibration strategy has been demonstrated for the determination of selected elements, i.e., Pb, Ag and T1 in a small amount of platinum nanoclusters. In on line isotope dilution analysis with LA-ICP-MS, an isotope emiched tracer solution was nebulized by the Aridus microconcentric nebulizer with desolvator. After about 180 seconds, laser ablation of the investigated platinum nanocluster sample was started and after an additional time of 180 seconds 2 % nitric acid nebulized instead of the tracer solution. The isotope ratios of lead ( Pb/ ° Pb), silver ( ° Ag/ ° Ag) and thallium ( ° T1/ ° T1) - with Cu/ Cu for internal standardization - were monitored during the whole experiment. The measuring time for one experiment was <10 min. 

A method for the accurate online ultratrace analysis of palladium in environmental samples (road dust and contaminated soil samples) by ICP-MS after separation of interferent cations by cation exchange chromatography was introduced by Hann and co-workers. ° Palladium was selectively adsorbed online onto a Cjg microcolumn which had been reversibly loaded with a complexing agent A,Al-diethyl-Al -benzoylthiourea (DEBT). The palladium complex formed was eluted with methanol and introduced into an ICP-SFMS via microconcentric nebulization with membrane desolvation. Isotope dilution analysis was employed for quantification purposes. ... 

Figure 6.19 Schematic setup of IA-ICP-MS with solution based calibration using microconcentric or ultrasonic nebulizer with membrane desolvator. (j. S. Becker et ai, Int. /. Mass Spectrom. 237, 13 (2004), reprinted by permission of Elsevier.)...

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