Desktop tool

Desktop tools address design and manufacturing concerns such as gate placement, injection time/rate, injection pressure, melt and mold temperatures, packing time and pressure, cooling time requirements, and machine size requirements. 

K., Chao, B., Ito, S., Clark, J., Coner, C., Waller, C., Kuki, A. PGVL Hub an integrated desktop tool for medicinal chemists to streamline design and synthesis of chemical libraries and singleton compounds, in (Zhou, J. Z., ed.) Chemical Library Design. Humana Press, New York, Chapter 15. 

PGVL Hub An Integrated Desktop Tool for Medicinal Chemists to Streamline Design and Synthesis of Chemical Libraries and Singleton Compounds... 

Key words Drug discovery, chem-informatics, molecular design, combinatorial chemistry, combinatorial library, synthesis protocol, PGVL, reactant, product, enumeration, filtering integration, workflow, streamline, desktop tool, software deployment. 

PGVL Hub is an integrated desktop tool which has been developed and globally deployed throughout Pfizer discovery research... 

Section V contains four chapters on library design tools. PGVL Hub described in Chapter 15 is an integrated desktop tool for molecular design including library design. It streamlines the design workflow from product structure formation to property... 

A distinction should immediately be made between information technology and information systems. The IT infrastrurture comprises the cables, hubs, switches and servers on which the systems run. It is also necessary to add to this the basic set of desktop tools, e.g., Miaosoft Office Professional . There can be cases where the business application drives major step changes in infrastructure direction. These instances, almost by definition, will be very large, strategic, high risk and infrequent opportunities. 

There are a variety of desktop or Web-based molecular editors available that can be used to generate a ligand file for a novel compound not found in any of the databases. The Web-based molecular editors allow users to sketch molecules in 2D, while desktop tools such as Avogadro [15] can draw molecules in 3D. 

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