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Desipramine ‘Pertofran

Desipramine is used for depression of various etiology and in particular for endogenous depression. Synonyms are norpramin and pertofrane. [Pg.108]

PertOfran desipramine. pertussis toxin (PTX) is elaborated by a bacterium Bordetella pertussis) and is a hexameric protein (4-5 subunits from A-B complex). It is a G-protein inactivator that binds to the ADP-ribosylation regulatory site of the G/Go family of subunits which couple negatively to adenylyl cyclase. The cellular responses blocked by PTX are varied, and typically include those due to 03 and opioid receptor type activation. The inactivation of this key regulatory unit explains some of the side-effects of whooping cough (caused by Bordetella pertussis) where production of this toxin is a main pathological factor. This toxin is an important pharmacological tool. [Pg.217]

Trade names Deprexan Nebril Nortimil Pertofran Pertofrane Petylyl PMS-Desipramine Indications Depression... [Pg.168]

Elavil (amitriptyline) Tofranil (imipramine) Pamelor/Aventyl (nortriptyline) Norpramin/Pertofrane (desipramine)... [Pg.84]

Tricyclics are the most commonly prescribed drag to treat major depression. Tricyclics include clomipramine HCl (Anafranil), desipramine HCl (Norpramin, Pertofrane), doxepin HCl (Sinequan), imipramine HCl (Tofranil), NortriptyMne HCl (Aventyl), Protriptyline HCl (Vivactil), and trimipramine maleate (Surmontil). [Pg.322]

See other pages where Desipramine ‘Pertofran is mentioned: [Pg.263]    [Pg.484]    [Pg.89]    [Pg.263]    [Pg.484]    [Pg.89]    [Pg.229]    [Pg.1730]    [Pg.1730]    [Pg.362]    [Pg.221]    [Pg.688]    [Pg.363]    [Pg.372]    [Pg.146]    [Pg.94]    [Pg.238]    [Pg.647]    [Pg.671]    [Pg.671]    [Pg.137]    [Pg.1730]    [Pg.1730]    [Pg.1730]    [Pg.1730]   
See also in sourсe #XX -- [ Pg.89 ]



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Desipramine

Pertofran

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