Design Wilks model

A qualified question is then whether or not the multicomponent models are really worthwhile in reactor simulations, considering the accuracy reflected by the flow, kinetics and equilibrium model parts involved. For the present multiphase flow simulations, the accuracy reflected by the flow part of the model is still limited so an extended binary approach like the Wilke model sufEce in many practical cases. This is most likely the case for most single phase simulations as well. However, for diffusion dominated problems multicomponent diffusion of concentrated ideal gases, i.e., for the cases where we cannot confidently designate one of the species as a solvent, the accuracy of the diffusive fluxes may be significantly improved using the Maxwell-Stefan approach compared to the approximate binary Fickian fluxes. The Wilke model might still be an option and is frequently used for catalyst pellet analysis. 

D., Smith, 1. R., Sore, N. E., Wilks, T.. Development of a new physicochemical model for brain penetration and its application to the design of centrally acting H2 receptor histamine antagonists. J. Med. Chem. 1988, 31, 656-671. 

Beger, R.D., Buzatu, D.A. and Wilkes, J.G. (2002) Combining NMR spectral and structural data to form models of polychlorinated dibenzodioxins, dibenzofurans, and biphenyls binding to the AhR. Journal of Computer-Aided Molecular Design, 16, 727-740. 

Another utility vehicle that reached international status was the British-designed Land Rover. Maurice Wilks was the chief designer at Rover at the end of World War II. He was using an ex-army Jeep on his estate and would need a replacement when the car wore out. He had several Jeeps taken apart at the Rover factory and then built a four-wheel-drive vehicle for the British market. Since there still were restrictions on steel, except for the export market, the body of the Land Rover was made of aluminium alloy. The prototype was built on a Jeep chassis in 1947 and the final model appeared in 1948. It was a success with British farmers and gradually moved into the general consumer market. 

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