Design of Synthetic Strategies

Thirdly, some of the derivatives provide protection of the functional group, and their preparation, chemical reactivity, and deprotection procedures may be of value in the design of synthetic strategies. 

In short, it is clear that gold makes an essential contribution to metallophilic interactions. Thus, the design of synthetic strategies to prepare systems with these bonds of unique versatility and flexibility must include gold as an essential building block. 

Our aim has been the construction of dendrimers that incorporate in their building blocks specific pieces of information such as the capability to absorb and emit visible light and to reversibly exchange electrons.To pursue this aim, we have designed a synthetic strategy to build up dendrimers based on luminescent and redox-active transition metal complexes. Species containing 4, 6, iP 10,2W7 28 gjjj 222930 metal-based units have already been obtained. We will see... 

For the design of synthetic routes based on protected hydrazides the appropriate choice of the protecting groups for the a-amino, A -hydrazide and side-chain functionalities is of critical importance, although the possibility offered by the azide procedure to apply the strategy of minimum protection significantly facilitates the problem of an orthogonal protection scheme. In Table 1 different examples of such protection schemes are listed. 

P should be as large as possible per unit of molecular volume (if increasing the size of the chromophore does not produce a disproportionately large increase in P, an alternative molecular design and synthetic strategy should be pursued). 

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