DESFERAL MESYLATE

Deferoxamine deferoxamine mesylate, desferal mesylate) is poorly absorbed after oral administration, and parenteral administration is required in most cases. For severe iron toxicity (serum iron levels >500 /rg/dL), the intravenous route is preferred. The drug is administered at 10-15 mg/kg/h by constant infusion. Faster rates of infusion (45 mg/kg/h) have been used in a few cases rapid boluses usually are associated with hypotension. Deferoxamine may be given intramuscularly in moderately toxic cases (serum iron 350-500 )ig/dL) at a dose of 50 mg/kg with a maximum dose of 1 g. Hypotension also can occur with the intramuscular route. 

F Desferal (Ciba-Geigy) J Desferal (Novartis-Takeda) mesylate)... 

A. Parenteral. Deferoxamine mesylate (Desferal), vials containing 500 mg of lyophilized powder. 

Desferal Vials (Desferoxamine mesylate). Novartis. US Prescribing informatioii, Februaiy... 

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