Dermatotoxicity

In summary, it can be reported that toxic cyanobacteria can produce neurotoxic, hepatotoxic, and dermatotoxic compounds that are a direct threat to animal and human water supplies. This threat increases as water bodies become more eutrophic, thus supporting higher production of toxic and nontoxic cyanobacteria. Presence of these potent natural product toxins poses an increasing threat to the maintenance of quality water supplies for agriculture, municipal, and recreational use. 

The dermatotoxicity of iAs is well established. Epidemiological studies identify an increased incidence of keratinocytic tumors associated with iAs exposure, as well as... 

Burleson, F. G. et al., Dermatotoxic chemical stimulate of c-jun and c-fos transcription and AP-1 DNA binding in human keratinocytes, Res. Commun. Mol. Pathol. Pharmacol.,... 

Casillas, R.P., Kiser, R.C. (2000). Therapeutic approaches to dermatotoxicity by sulfurmustard. I. Modulaton of sulfur mustard-induced cutaneous injury in the mouse ear vesicant model. J. Appl. Toxicol. 20, Suppl. 1 SI45-51. 

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