2 -deoxyguanosine reaction with hydroxyl radical

The reaction of 2 -deoxyguanosine with hydroxyl radicals gives two main products 275 and 276, which have been the subject of a detailed study by... 

Chatgilialoglu C, D Angelantonio M, Kciuk G, Bobrowski K. New insights into the reaction paths of hydroxyl radicals with 2 -deoxyguanosine. Chem Res Toxicol. 2011 24 2200-2206. 

Velikyan I, Acharya S, Trifonova A, Foldesi A, Chattopadhyaya J (2001) The pffas of 2 -hydroxyl group in nudeosides and nucleotides. J Am Chem Soc 123 2893-2894 Veltwisch D, Asmus K-D (1982) On the reaction of methyl and phenyl radicals with p-benzoquinone in aqueous solution. J Chem Soc Perkin Trans 2 1147-1152 Vialas C, Pratviel G, Claparols C, Meunier B (1998) Efficient oxidation of 2 -deoxyguanosine by Mn-TMPyP/KHSOs to imidazolone dlz without formation of 8-oxo-dG. J Am Chem Soc 120 11548-11553... 

Vanadium(IV) caused molecular oxygen-dependent 2 -deoxyguanosine hydroxylation and DNA strand breaks (Shi et al. 1996). ESR spin trapping measurements demonstrated that the reaction of vana-dium(IV) with HjOj generated HO radicals, which were inhibited by the metal ion chelators, diethyle-netriaminepentaacetic acid (DTPA) and deferoxamine. UV-visible measurements indicated that 2 -... 

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