Demyelination multiple sclerosis-related

One was a known case of pre-existent multiple sclerosis but the other had no history of neurological diseases. Both had HLA haplotype DR2 and B7, which are associated with multiple sclerosis. A causal link between immunization and demyelination cannot be established from these two case reports, but the time interval would fit a proposed immunological mechanism. In addition, the Centers for Disease Control (CDC) in Atlanta, Georgia, received reports on four cases of chronic demyelinating disease. Several other reports describe related conditions or other forms of neurological disorder. 

Nervous system Infusion-related headache affected more than 50% of treated individuals in a cohort of patients with multiple sclerosis [138 ]. Anxiety, syncope, vertigo, dizziness, tremor, paresthesia, and hypesthe-sia are common undesirable reactions during treatment or within 30 days after the completion of treatment with alemtuzumab. Guil-lain-Barre syndrome and its chronic form, chronic inflammatory demyelinating polyradiculoneuropathy, have also been reported. 

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