Dementia syndrome

Gortical Lewy body disease produces a clinically distinct dementia syndrome. Two of the three core features of this syndrome involve abnormalities of consciousness, firstly marked fluctuations in consciousness (usually most apparent in applied cognitive performance) and secondly psychosis, in... 

Wolkowitz OM, Lupien SJ, Bigler E, et al. The steroid dementia syndrome an unrecognized complication of glucocorticoid treatment. Ann NYAcadSci. 2004 1032 191-194. 

Although it might be expected that the incidence of the primary sleep disorders would increase in demented patients relative to age-matched controls because of the CNS dysfunction underlying these disorders, studies comparing the rates of sleep apnea in dementia patients and aged controls have not found consistent differences. Nevertheless, these conditions may interact with the dementia syndrome to further worsen sleep quality as well as cognitive and functional abilities. For example, some studies have shown that sleep apnea is associated with increased morning confusion in AD patients. 

There is no blood test or X-ray to diagnose Alzheimer s-type dementia per se, but there are tests for causes of dementia syndromes that may at first look like Alzheimer s disease, and often those causes are treatable. 

Dementia Syndromes Parkinsonism Plus Syndromes Neuromuscular Disorders Genetic/Metabolic Disorders... 

Ingestion > inhalation. Osteomalacia (softening of bones). Neurotoxicity effects include neurofibrillary tangles behavioral changes possible causative agent of Alzheimer s disease, some human dementia syndromes. Exposure to Al dusts can trigger lung fibrosis. 

Crapper MacLachlan D. R., MacLachlan C. D., Krishnan B., Krishnan S. S., Dalton A. J., and Steele J. C. (1989) Aluminum and calcium in soil and food from Guam, Palau, and Jamaica implications for amyotrophic lateral sclerosis and parkinsonism-dementia syndromes of Guam. Environ. Geochem. Health 11, 45-53. 

Dementia syndromes Alzheimer disease, diffuse Lewy body disease, frontotemporal dementia... 

Sideman S, Manor D. The dialysis dementia syndrome and aluminum intoxication. Nephron 1982 31(1) 1-10. 

A dementia syndrome characterized by an insidious progressive decline in memory, cognition, behavioral... 

Two patients who had been taking methyldopa 1 to 1.5 g daily for hypertension, without problems, developed a dementia syndrome (cognitive disabilities, loss of memory, disorientation, etc.) within 3 days of starting to take haloperidol 6 to 8 mg daily for anxiety. The symptoms totally cleared within 72 hours of stopping the haloperidol. Another patient treated with haloperidol for schizophrenia, and methyldopa for hypertension, became very irritable and aggressive. When the methyldopa was replaced with hydrochlorothiazide, the patient s behaviour improved dramatically. ... 

Manckoundia P, Disson-Dautriche A, Rouaud O, Richard D, Tavernier-Vidal B, Pfitzenmeyer P. Dementia syndrome in an elderly subject related to valproic acid use a case report. Rev Med Interne 2008 29(10) 827-9. 

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