Dementia cholinergic approaches

Nicotinic Cholinergic Approaches to Cognitive Enhancement in the Dementias... 

Since many articles have recently appeared summarizing cholinergic approaches to the treatment of dementia,22-26 will only briefly review this active research area and then discuss other chemotherapeutic approaches which show promise In the treatment of cognitive dysfunction. 

The last approach, then, is to increase cholinergic activity by increasing the level of the substrate for choline acetyltransferase. Such precursor therapy aims to augment individual neuronal capacity. There are numerous studies in the literature designed to document the effectiveness of such dietary precursor therapy in patients with dementia. Unfortunately, the results have been generally discouraging. 

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