Degradation with loss

Bacteria selected for growth with bis-(3-pentflnorophenylpropy)-sulfide as sulfur source are able to use dimethyl sulfoxide, dibenzyl snlfide, and some long-chain disulfides as sources of sulfur (van Hamme et al. 2004). Degradation takes place by oxidation to the sulfone, scission of the C-S bond to an alkanol, and an alkyl sulfinate that is degraded with loss of the snlfnr, which is nsed for growth. 

For 205 (55% exo-CFj, 45% endo-CFj) the exo-isomer is more reactive so that if polymerization is incomplete, the residual monomer is enriched in the other isomer539. Polymers of 206 have a narrow MWD if initiated by 7 in THF. The polymer has a T% of 110°C and decomposes at 300 °C losing two molecules of acetic acid per repeat unit. It is also readily hydrolysed to the polydiol, which is soluble in CF3COOH/CHCI3 and degrades with loss of water at 300 °C485. 

Racemic or achiral a-azido acids are synthesized by direct azide substitution on commercially available a-bromo carboxylic acids or by radical bromination of carboxylic acids followed by azide substitution. In general, azido acids are stored in the dark to avoid photolytic degradation with loss of nitrogen temperatures above 50 °C should be avoided. Radical a-bromination of a-branched carboxylic acids as required for the synthesis of a,a-dialkyl or a,a-diaryl amino acids is performed with A-bromosuccinimide. This is followed by nucleophilic substitution with sodium azide or other azide donors, e.g. tetrabutylannmonium azide, to produce achiral or racemic a-azido-a,a-diaIkyl or a-azido-a,a-diaryl carboxylic acids (Scheme 74).Synthesis of more sterically hindered a,a-disubstituted azido acids leads to hydroxy compounds when prolonged reaction times are required and not sufficient care is taken to operate under dry conditions and an inert atmosphere.t ... 

The polymerization of Polymer 10 reached its maximum torque in 7 minutes (390 meter-grams) then died and began to degrade with loss of melt viscosity, even at this low polymer melt viscosity level and familiar polymerization temperature. Ethylene glycol chain extended polymers have been anomalous polymerizations and polymers in our experience due, we believe, to abnormal chemistry that can occur during their preparation. 

Hydrocarbons from a,j5-ethylenenitriles Degradation with loss of 1 C-atom s. 4, 120 ... 

Ketones from aldehydes Degradation with loss of 1 C>atom... 

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