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Degradation, early detection intensity

The mRNA level of a bioprocess-relevant gene can be used as an early measure of its expression status. A simple but labor-intensive offline technique for the mRNA analysis of one or a limited number of genes is Northern blotting. Following the separation of the RNA sample in a polyacrylamide gel, the RNA is blotted on a membrane and detected by the hybridization of labeled sequence-specific probes. This technique does not only allow a quantitative analysis of the mRNA level but also gives information about the length and potential degradation products of the RNA. [Pg.3906]

Chromatographic Analysis and Total Luminescence Intensity as Tools for Early Degradation Detection and Degradation State Estimation... [Pg.307]

See other pages where Degradation, early detection intensity is mentioned: [Pg.370]    [Pg.98]    [Pg.90]    [Pg.150]    [Pg.100]    [Pg.378]    [Pg.249]    [Pg.9]    [Pg.185]    [Pg.557]    [Pg.236]    [Pg.221]    [Pg.24]    [Pg.307]    [Pg.308]    [Pg.314]    [Pg.88]   


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Degradation detection

Degradation, early detection

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